Publication detail

Diffusion behavior of analyte molecules in a nanoporous matrix created from polystyrene nanoparticles

KOŠELOVÁ, Z.

Original Title

Diffusion behavior of analyte molecules in a nanoporous matrix created from polystyrene nanoparticles

Type

conference paper

Language

English

Original Abstract

This study investigates the diffusion behavior of analyte molecules in a nanoporous matrix of polystyrene particles. Two approaches, steady-state current and potential step chronoamperometry were employed to calculate diffusion coefficients and compare the effect of nanoporous matrices with different diameter of pores and different method of immobilization of enzyme. Pores were created with close packing of polystyrene nanoparticles. The covalent and cross-linking immobilization were used to immobilize the enzyme. Chronoamperometric measurement was applied to detect analyte. The study found that the presence of nanoporous matrices immobilized on p-lysine affects diffusion. The potential step chronoamperometry method showed the improvement of diffusion. This study provides insight into the diffusion behavior of analyte molecules in nanoporous matrices, which can be useful in optimizing the design of amperometric biosensors.

Keywords

Diffuse coefficient, nanoporous matrix, potential step chronoamperometry, polystyrene nanoparticles, steady-state current

Authors

KOŠELOVÁ, Z.

Released

25. 4. 2023

ISBN

978-80-214-6154-3

Book

Proceedings II of the 29th Student EEICT 2023 (Selected Papers)

Edition

1

ISBN

2788-1334

Periodical

Proceedings II of the Conference STUDENT EEICT

State

Czech Republic

Pages from

248

Pages to

252

Pages count

5

BibTex

@inproceedings{BUT183416,
  author="Zuzana {Košelová}",
  title="Diffusion behavior of analyte molecules in a nanoporous matrix
created from polystyrene nanoparticles",
  booktitle="Proceedings II of the 29th Student EEICT 2023 (Selected Papers)",
  year="2023",
  series="1",
  journal="Proceedings II of the Conference STUDENT EEICT",
  pages="248--252",
  isbn="978-80-214-6154-3",
  issn="2788-1334"
}