Publication detail

Poly(3-hydroxybutyrate) based materials for 3D printing in medical applications

KROBOT, Š. MELČOVÁ, V. PŘIKRYL, R.

Original Title

Poly(3-hydroxybutyrate) based materials for 3D printing in medical applications

Type

abstract

Language

English

Original Abstract

One of the most advanced approaches used in contemporary regenerative medicine is tissue engineering. The key role in tissue engineering is played by a porous structure (scaffold), which serves as a support for cells and is then integrated into the human body. The scaffold must have a suitable porosity and 3D structure for the cells to grow through the entire volume of it and form new tissue. In recent years, a method of 3D printing is capturing attention in the bone tissue engineering field as it allows complex tailor-made structures to be produced in a time and cost-effective manner for every specific case and patient. Some bioplastics, such as polylactic acid, poly(3-hydroxybutyrate), or polycaprolactone are appealing not only for their environmental friendliness but also for their biocompatibility. The work focuses on research on 3D printing and testing of P3HB-based scaffolds for bone tissue engineering. Three polymer blends were prepared based on either commercial poly(3-hydroxybutyrate) or P3HB from the chloroform-free route, poly(lactic acid) and polycaprolactone, oligomeric adipate ester plasticizer, and tricalcium phosphate as a bioactive filler, and processed into the form of 3D printing filaments.

Keywords

3D printing; FDM; poly(3-hydroxybutyrate); bone tissue engineering; scaffold; biocompatibility; polycaprolactone; polylactic acid

Authors

KROBOT, Š.; MELČOVÁ, V.; PŘIKRYL, R.

Released

30. 11. 2022

Publisher

Vysoké učení technické v Brně, Fakulta chemická

Location

Purkyňova 464/118, 612 00 Brno

ISBN

978-80-214-6117-8

Book

Sborník abstraktů ze studentské odborné konference "Chemistry is life 2022"

Edition number

první

Pages from

37

Pages to

38

Pages count

2

URL

https://www.fch.vut.cz/vav/konference/sok/vystupy/sbornik-abstraktu-2022-2-a4-final-pdf-p231619

BibTex

@misc{BUT183590,
  author="Štěpán {Krobot} and Veronika {Melčová} and Radek {Přikryl}",
  title="Poly(3-hydroxybutyrate) based
materials for 3D printing in medical
applications",
  booktitle="Sborník abstraktů ze studentské odborné konference {"}Chemistry is life 2022{"}",
  year="2022",
  edition="první",
  pages="37--38",
  publisher="Vysoké učení technické v Brně, Fakulta chemická",
  address="Purkyňova 464/118, 612 00 Brno",
  isbn="978-80-214-6117-8",
  url="https://www.fch.vut.cz/vav/konference/sok/vystupy/sbornik-abstraktu-2022-2-a4-final-pdf-p231619",
  note="abstract"
}