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LANGOVÁ, D. CÓRDOBA, M. SORRECHIA, R. HOOVÁ, J. SVOBODA, Z. MIKULÍKOVÁ, R. CORREA, M. PIETRO, R. MÁROVÁ, I.
Original Title
Achyrocline satureioides Hydroalcoholic Extract as a Hypoallergenic Antimicrobial Substitute of Natural Origin for Commonly Used Preservatives in Cosmetic Emulsions
Type
journal article in Web of Science
Language
English
Original Abstract
Achyrocline satureioides is a South American herb used in traditional medicine to treat a wide range of ailments. The healing and antimicrobial effects of this plant have already been covered by many studies, which have confirmed its beneficial effects on human health. In this study, the antimicrobial effect of A. satureioides hydroalcoholic extract against Escherichia coli ATCC10536, Staphylococcus aureus ATCC25923, Staphylococcus epidermidis ATCC12228 and Lactobacillus acidophilus INCQS00076 was determined. The cytotoxicity of the extract was tested on human HaCaT keratinocytes showing very favourable effects on the proliferation and renewal of keratinocytes. According to the results of the HPLC and GC-MS analyses, the lyophilized extract contained only a minimal amount of fragrance allergens. The extract was then used in two cosmetic formulations, and one of them showed a significant synergistic interaction with other cosmetic components. We suggest the use of A.satureioides hydroalcoholic extract as a suitable antimicrobial component of natural origin for cosmetic preparations as a substitute for commonly used preservatives that can cause skin irritation and as a material with its own biological activity.
Keywords
Achyrocline satureioides; hydroalcoholic extract; natural bioactive compounds; flavonoids; antimicrobial; cosmetic emulsion; fragrance allergens; HaCaT; cytotoxicity
Authors
LANGOVÁ, D.; CÓRDOBA, M.; SORRECHIA, R.; HOOVÁ, J.; SVOBODA, Z.; MIKULÍKOVÁ, R.; CORREA, M.; PIETRO, R.; MÁROVÁ, I.
Released
18. 5. 2023
Publisher
MDPI
Location
BASEL, ŠVÝCARSKO
ISBN
2223-7747
Periodical
Plants
Year of study
12
Number
10
State
Swiss Confederation
Pages from
1
Pages to
15
Pages count
URL
https://www.mdpi.com/2223-7747/12/10/2027
Full text in the Digital Library
http://hdl.handle.net/11012/244947
BibTex
@article{BUT183617, author="Denisa {Langová} and Maria Angélica Mera {Córdoba} and Rodrigo {Sorrechia} and Julie {Hoová} and Zdeněk {Svoboda} and Renata {Mikulíková} and Marcos Antonio {Correa} and Rosemeire Cristina Linhari R. {Pietro} and Ivana {Márová}", title="Achyrocline satureioides Hydroalcoholic Extract as a Hypoallergenic Antimicrobial Substitute of Natural Origin for Commonly Used Preservatives in Cosmetic Emulsions", journal="Plants", year="2023", volume="12", number="10", pages="15", doi="10.3390/plants12102027", issn="2223-7747", url="https://www.mdpi.com/2223-7747/12/10/2027" }