Publication result detail

Microfluidic trends in drug screening and drug delivery

Jianguo Feng, Jiri Neuzil, Andreas manz, Ciprian Iliescu, Pavel Neuzil

Original Title

Microfluidic trends in drug screening and drug delivery

English Title

Microfluidic trends in drug screening and drug delivery

Type

WoS Article

Original Abstract

The low probability of a drug candidate's clinical success, the time consumed and the high cost of bringing a drug from concept to market emphasizes the need for new approaches to drug discovery. Recent innovations in microfluidic technologies, including organ-on-a-chip, droplet microfluidics and high-throughput screening are revealing the potential of these platforms to address some of these challenges, due to the small volume of samples consumed, short processing time, and improved process control. Here, we review selected recent progress in the development and application of microfluidic technologies in drug screening and drug delivery, highlighting the trends and associated challenges.

English abstract

The low probability of a drug candidate's clinical success, the time consumed and the high cost of bringing a drug from concept to market emphasizes the need for new approaches to drug discovery. Recent innovations in microfluidic technologies, including organ-on-a-chip, droplet microfluidics and high-throughput screening are revealing the potential of these platforms to address some of these challenges, due to the small volume of samples consumed, short processing time, and improved process control. Here, we review selected recent progress in the development and application of microfluidic technologies in drug screening and drug delivery, highlighting the trends and associated challenges.

Keywords

Microfluidic technologies; Drug screeningDrug delivery; Drug discovery

Key words in English

Microfluidic technologies; Drug screeningDrug delivery; Drug discovery

Authors

Jianguo Feng, Jiri Neuzil, Andreas manz, Ciprian Iliescu, Pavel Neuzil

RIV year

2024

Released

01.01.2023

Publisher

Elsevier

Location

Netherlands

ISBN

0165-9936

Periodical

TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Volume

158

Number

116821

State

United Kingdom of Great Britain and Northern Ireland

Pages count

18

URL

https://www.sciencedirect.com/science/article/abs/pii/S0956566323002610?via%3Dihub

BibTex

@article{BUT183689,
  author="Pavel {Neužil}",
  title="Microfluidic trends in drug screening and drug delivery
",
  journal="TRAC-TRENDS IN ANALYTICAL CHEMISTRY",
  year="2023",
  volume="158",
  number="116821",
  pages="18",
  doi="10.1016/j.trac.2022.116821",
  issn="0165-9936",
  url="https://www.sciencedirect.com/science/article/abs/pii/S0956566323002610?via%3Dihub"
}