Publication detail

Effective EEG Feature Selection for Interpretable MDD (Major Depressive Disorder) Classification

MRÁZEK, V. JAWED, S. ARIF, M. MALIK, A.

Original Title

Effective EEG Feature Selection for Interpretable MDD (Major Depressive Disorder) Classification

Type

conference paper

Language

English

Original Abstract

In this paper, we propose an interpretable electroencephalogram (EEG)-based solution for the diagnostics of major depressive disorder (MDD). The acquisition of EEG experimental data involved 32 MDD patients and 29 healthy controls. A feature matrix is constructed involving frequency decomposition of EEG data based on power spectrum density (PSD) using the Welch method. Those PSD features were selected, which were statistically significant. To improve interpretability, the best features are first selected from feature space via the non-dominated sorting genetic (NSGA-II) evolutionary algorithm. The best features are utilized for support vector machine (SVM), and k-nearest neighbors (k-NN) classifiers, and the results are then correlated with features to improve the interpretability. The results show that the features (gamma bands) extracted from the left temporal brain regions can distinguish MDD patients from control significantly. The proposed best solution by NSGA-II gives an average sensitivity of 93.3%, specificity of 93.4% and accuracy of 93.5%. The complete framework is published as open-source at https://github.com/ehw-fit/eeg-mdd.

Keywords

electroencephalogram (EEG), feature extraction, major depressive disorder

Authors

MRÁZEK, V.; JAWED, S.; ARIF, M.; MALIK, A.

Released

14. 4. 2023

Publisher

Association for Computing Machinery

Location

Lisbon

ISBN

979-8-4007-0119-1

Book

GECCO 2023 - Proceedings of the 2023 Genetic and Evolutionary Computation Conference

Pages from

1427

Pages to

1435

Pages count

9

URL

https://dl.acm.org/doi/10.1145/3583131.3590398

Full text in the Digital Library

http://hdl.handle.net/11012/244320

BibTex

@inproceedings{BUT185129,
  author="Vojtěch {Mrázek} and Soyiba {Jawed} and Muhammad {Arif} and Aamir Saeed {Malik}",
  title="Effective EEG Feature Selection for Interpretable MDD (Major Depressive Disorder) Classification",
  booktitle="GECCO 2023 - Proceedings of the 2023 Genetic and Evolutionary Computation Conference",
  year="2023",
  pages="1427--1435",
  publisher="Association for Computing Machinery",
  address="Lisbon",
  doi="10.1145/3583131.3590398",
  isbn="979-8-4007-0119-1",
  url="https://dl.acm.org/doi/10.1145/3583131.3590398"
}

Documents

GECCO_23_eeg_mdd_final.pdf