Publication detail

Flexible and transparent gum Karaya-based hydrogel film as a matrix for wound healing enriched with antibacterial bacteriophages and antiseptics to suppress and eliminate non-healing bacterial infections

ČERNÁ, E. BRTNÍKOVÁ, J. VACEK, L. RŮŽIČKA, F. LIPOVÝ, B. KOMÁRKOVÁ, M. PLEVKA, P. PANTŮČEK, R. VOJTOVÁ, L.

Original Title

Flexible and transparent gum Karaya-based hydrogel film as a matrix for wound healing enriched with antibacterial bacteriophages and antiseptics to suppress and eliminate non-healing bacterial infections

Type

abstract

Language

English

Original Abstract

Polysaccharide gum Karaya is a promising natural material for tissue engineering as it possesses high biocompatibility, non-toxicity, and potential antimicrobial properties. Gum Karaya-based hydrogel films fabricated via freeze-drying form transparent and flexible hydrogel with an excellent mechanical property suitable for direct use in wound healing. Subsequent enrichment with antimicrobial agents increases the multifunctionality of the hydrogel. It makes it possible to battle resistant gram-positive S. aureus using bacteriophages or antiseptic octenidine dihydrochloride, which can suppress gram-negative E. coli.

Keywords

gum Karaya, bacteriophage, antiseptics, octenidine dihydrochloride, wound healing, antimicrobial, hydrogel

Authors

ČERNÁ, E.; BRTNÍKOVÁ, J.; VACEK, L.; RŮŽIČKA, F.; LIPOVÝ, B.; KOMÁRKOVÁ, M.; PLEVKA, P.; PANTŮČEK, R.; VOJTOVÁ, L.

Released

9. 11. 2023

Location

Praha

Pages from

10

Pages to

10

Pages count

1

BibTex

@misc{BUT185328,
  author="Eva {Černá} and Jana {Brtníková} and Lukáš {Vacek} and Filip {Růžička} and Břetislav {Lipový} and Marie {Komárková} and Pavel {Plevka} and Roman {Pantůček} and Lucy {Vojtová}",
  title="Flexible and transparent gum Karaya-based hydrogel film as a matrix for wound healing enriched with antibacterial bacteriophages and antiseptics to suppress and eliminate non-healing bacterial infections",
  booktitle="19th International Conference on Polysaccharides-Glycoscience",
  year="2023",
  pages="10--10",
  address="Praha",
  note="abstract"
}