Publication detail

A minireview on the bioinformatics analysis of mobile gene elements in microbiome research

SCHWARZEROVÁ, J. LABANAVA, A. RYCHLÍK, I. VARGA, M. ČEJKOVÁ, D.

Original Title

A minireview on the bioinformatics analysis of mobile gene elements in microbiome research

Type

journal article - other

Language

English

Original Abstract

The horizontal transfer of mobile gene elements between bacteria plays a crucial role in their evolutionary dynamics. Additionally, it enables the accumulation and dissemination of genes conferring antibiotic and heavy-metal resistance, and thus contributes to the worldwide emergence and spread of drug-resistance pathogens. This process is instrumental in maintaining genetic diversity within bacterial populations and facilitates their adaptation to novel environments. It allows bacteria to acquire genes responsible for the synthesis of enzymes that utilize alternative energy sources and substrates. Furthermore, bacteria can acquire genes associated with toxin production and increased virulence. Horizontal gene transfer serves as a pivotal mechanism in bacterial evolution, enabling the acquisition of novel genetic information and enhancing their capabilities. However, the proper detection and identification of horizontally transferred genes at the microbiome scale is challenging, whether using wet-lab experime

Keywords

horizontal gene transfer, bacterial genomics, mobilome, microbiome, genome analysis

Authors

SCHWARZEROVÁ, J.; LABANAVA, A.; RYCHLÍK, I.; VARGA, M.; ČEJKOVÁ, D.

Released

11. 10. 2023

Publisher

Frontiers

ISBN

2813-6144

Periodical

Frontiers in Bacteriology

Year of study

2

Number

1

State

United States of America

Pages count

8

URL

https://www.frontiersin.org/articles/10.3389/fbrio.2023.1275910/full

Full text in the Digital Library

http://hdl.handle.net/11012/245103

BibTex

@article{BUT185424,
  author="Jana {Schwarzerová} and Anastasiya {Labanava} and Ivan {Rychlík} and Margaret {Varga} and Darina {Čejková}",
  title="A minireview on the bioinformatics analysis of mobile gene elements in microbiome research",
  journal="Frontiers in Bacteriology",
  year="2023",
  volume="2",
  number="1",
  pages="8",
  doi="10.3389/fbrio.2023.1275910",
  issn="2813-6144",
  url="https://www.frontiersin.org/articles/10.3389/fbrio.2023.1275910/full"
}