Publication detail

Enhancing protein release from bone scaffolds via encapsulation into either liposomes or polymersomes

KADLECOVÁ, Z. LYSÁKOVÁ, K. HLINÁKOVÁ, K. MENČÍK, P. VOJTOVÁ, L.

Original Title

Enhancing protein release from bone scaffolds via encapsulation into either liposomes or polymersomes

Type

abstract

Language

English

Original Abstract

In the proposed research, the pro-healing, as well as antibacterial proteins, were incorporated into liposomes and two types of polymersomes, offering additional safeguarding for the protein throughout the bone scaffold curing process and ensuring more precise analysis of the protein‘s release kinetics from the scaffold onto the wound site. The term „polymersome“ for vesicles made from block copolymers was coined in 1999 (2). Polymersomes are similar to liposomes, vesicles formed from naturally occurring lipids. While having many of the properties of natural liposomes, polymersomes exhibit increased stability and reduced permeability. Furthermore, the use of synthetic polymers enables designers to manipulate the characteristics of the membrane and thus control permeability, release rates, stability and other properties of the polymersome. Both proteins were encapsulated in various types of particles, including lipidbased, biopolymer-based, and synthetic polymer-based particles. The encapsulation m

Keywords

prohealing protein, bone scaffolds, protein release

Authors

KADLECOVÁ, Z.; LYSÁKOVÁ, K.; HLINÁKOVÁ, K.; MENČÍK, P.; VOJTOVÁ, L.

Released

25. 5. 2024

Publisher

České vysoké učení technické v Praze

Location

Praha

ISBN

978-80-01-07293-6

Book

Bioimplantologie a regenerativní medicína 2024

Edition

1

Edition number

1

Pages from

37

Pages to

37

Pages count

1

URL

https://921c88450d.clvaw-cdnwnd.com/17e12706bb26b88046060a8921d16f31/200000499-73ed673ed8/bioimplantologie_2024_sbornik.pdf?ph=921c88450d

BibTex

@misc{BUT188691,
  author="Zuzana {Kadlecová} and Klára {Tušlová} and Kristýna {Hlináková} and Přemysl {Menčík} and Lucy {Vojtová}",
  title="Enhancing protein release from bone scaffolds via encapsulation
into either liposomes or polymersomes",
  booktitle="Bioimplantologie a regenerativní medicína 2024",
  year="2024",
  series="1",
  edition="1",
  pages="37--37",
  publisher="České vysoké učení technické v Praze",
  address="Praha",
  isbn="978-80-01-07293-6",
  url="https://921c88450d.clvaw-cdnwnd.com/17e12706bb26b88046060a8921d16f31/200000499-73ed673ed8/bioimplantologie_2024_sbornik.pdf?ph=921c88450d",
  note="abstract"
}