Publication detail

Ultrathin TiO2 Coatings via Atomic Layer Deposition Strongly Improve Cellular Interactions on Planar and Nanotubular Biomedical Ti Substrates

ČAPEK, J. SEPÚLVEDA SEPÚLVEDA, L. BÁČOVÁ, J. RODRIGUEZ PEREIRA, J. ZAZPE MENDIOROZ, R. ČIČMANCOVÁ, V. NÝVLTOVÁ, P. HANDL, J. KNOTEK, P. BAISHYA, K. SOPHA, H. ŠMÍD, L. ROUŠAR, T. MACÁK, J.

Original Title

Ultrathin TiO2 Coatings via Atomic Layer Deposition Strongly Improve Cellular Interactions on Planar and Nanotubular Biomedical Ti Substrates

Type

journal article in Web of Science

Language

English

Original Abstract

This work aims to investigate the chemical and/or structural modification of Ti and Ti-6Al-4V (TiAlV) alloy surfaces to possess even more favorable properties toward cell growth. These modifications were achieved by (i) growing TiO2 nanotube layers on these substrates by anodization, (ii) surface coating by ultrathin TiO2 atomic layer deposition (ALD), or (iii) by the combination of both. In particular, an ultrathin TiO2 coating, achieved by 1 cycle of TiO2 ALD, was intended to shade the impurities of F- and V-based species in tested materials while preserving the original structure and morphology. The cell growth on TiO2-coated and uncoated TiO2 nanotube layers, Ti foils, and TiAlV alloy foils were compared after incubation for up to 72 h. For evaluation of the biocompatibility of tested materials, cell lines of different tissue origin, including predominantly MG-63 osteoblastic cells, were used. For all tested nanomaterials, adding an ultrathin TiO2 coating improved the growth of MG-63 cells and other cell lines compared with the non-TiO2-coated counterparts. Here, the presented approach of ultrathin TiO2 coating could be used potentially for improving implants, especially in terms of shading problematic F- and V-based species in TiO2 nanotube layers.

Keywords

TiO2 nanotube layers; Ti foils; Ti-6Al-4V alloy; atomic layer deposition; cellproliferation; MG-63 cells

Authors

ČAPEK, J.; SEPÚLVEDA SEPÚLVEDA, L.; BÁČOVÁ, J.; RODRIGUEZ PEREIRA, J.; ZAZPE MENDIOROZ, R.; ČIČMANCOVÁ, V.; NÝVLTOVÁ, P.; HANDL, J.; KNOTEK, P.; BAISHYA, K.; SOPHA, H.; ŠMÍD, L.; ROUŠAR, T.; MACÁK, J.

Released

26. 1. 2024

Publisher

AMER CHEMICAL SOC

Location

WASHINGTON

ISBN

1944-8252

Periodical

ACS applied materials & interfaces

Year of study

16

Number

5

State

United States of America

Pages from

5627

Pages to

5636

Pages count

10

URL

https://pubs.acs.org/doi/10.1021/acsami.3c17074

BibTex

@article{BUT188929,
  author="Jan {Čapek} and Lina Marcela {Sepúlveda Sepúlveda} and Jana {Báčová} and Jhonatan {Rodriguez Pereira} and Raúl {Zazpe Mendioroz} and Veronika {Čičmancová} and Pavlína {Nývltová} and Jiří {Handl} and Petr {Knotek} and Kaushik {Baishya} and Hanna Ingrid {Sopha} and Lenka {Šmíd} and Tomáš {Roušar} and Jan {Macák}",
  title="Ultrathin TiO2 Coatings via Atomic Layer Deposition Strongly Improve Cellular Interactions on Planar and Nanotubular Biomedical Ti Substrates",
  journal="ACS applied materials & interfaces",
  year="2024",
  volume="16",
  number="5",
  pages="5627--5636",
  doi="10.1021/acsami.3c17074",
  issn="1944-8252",
  url="https://pubs.acs.org/doi/10.1021/acsami.3c17074"
}