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Publication detail
FIALOVÁ, A. SEDLÁŘ, K.
Original Title
BacSeqer: Read simulator for bacterial RNA-Seq
Type
conference paper
Language
English
Original Abstract
The RNA-Seq method has become a key tool in transcriptomics, providing deep insight into the genetic functioning of organisms. It is essential for understanding how genes are expressed, for discovering new gene variants and for understanding pathologies at the genetic level. RNA-Seq simulators are great for testing and validating bioinformatics tools, they offer a way to compare different computational algorithms and allow examining different sequencing protocols, parameter settings and sample sizes to ensure the most efficientuse of resources. This study introduces BacSeqer, an RNA-Seq simulator specifically designed for bacterial transcriptomes with the aim of producing data that faithfully resembles those obtained in real experiments. It allows to take into account the specificities of the bacterial genome, especially an existence of only exons and their organization in operons that are not normally present in eukaryotes.
Keywords
RNA-Seq; simulation; sequencing; bacteria; gene expression
Authors
FIALOVÁ, A.; SEDLÁŘ, K.
Released
24. 4. 2024
ISBN
978-80-214-6230-4
Book
Proceedings II of the 30 th Conference STUDENT EEICT 2024
Edition
1
Pages from
12
Pages to
15
Pages count
4
BibTex
@inproceedings{BUT189095, author="Adéla {Fialová} and Karel {Sedlář}", title="BacSeqer: Read simulator for bacterial RNA-Seq", booktitle="Proceedings II of the 30 th Conference STUDENT EEICT 2024", year="2024", series="1", pages="12--15", isbn="978-80-214-6230-4" }