Publication detail

Exploring Speech Profiles in Parkinson's Disease Patients on Long - Term Dopaminergic Medication

KOVÁČ, D. NOVOTNÝ, K. MEKYSKA, J. BRABENEC, L. KOŠŤÁLOVÁ, M. REKTOROVÁ, I.

Original Title

Exploring Speech Profiles in Parkinson's Disease Patients on Long - Term Dopaminergic Medication

Type

conference paper

Language

English

Original Abstract

Hypokinetic dysarthria (HD), prevalent in Parkin-son's disease (PD), is characterized by reduced motor movement, leading to speech and voice impairments. The effectiveness of dopamine therapy varies, and symptoms may change over time. To explore the HD in patients on medication, we conducted hierarchical clustering to categorize 83 PD patients using the acoustic features extracted from recorded text reading, sustained phonation, and diadochokinetic task. We then compared these clusters to a group of 44 healthy controls. Regardless of the medication dosage and PD duration, patients displayed three distinct speech profiles: articulatory; respiratory-prosodic; and another more complex/severe regarding the number of HD do-mains affected. The newly identified profiles exhibit distinctions from previously defined speech subtypes in de novo PD patients. No differences in clinical scores were observed among the newly identified profiles, suggesting uniformity in clinical presentation despite distinct speech characteristics.

Keywords

Acoustic Analysis; Clustering; Dopamine Therapy; Hypokinetic Dysarthria, Parkinson’s Disease, Speech Profiles

Authors

KOVÁČ, D.; NOVOTNÝ, K.; MEKYSKA, J.; BRABENEC, L.; KOŠŤÁLOVÁ, M.; REKTOROVÁ, I.

Released

30. 7. 2024

Publisher

IEEE

ISBN

979-8-3503-6559-7

Book

2024 47th International Conference on Telecommunications and Signal Processing (TSP)

Pages from

270

Pages to

273

Pages count

4

URL

https://doi.org/10.1109/TSP63128.2024.10605914

BibTex

@inproceedings{BUT189257,
  author="Daniel {Kováč} and Kryštof {Novotný} and Jiří {Mekyska} and Luboš {Brabenec} and Milena {Košťálová} and Irena {Rektorová}",
  title="Exploring Speech Profiles in Parkinson's Disease Patients on Long - Term Dopaminergic Medication",
  booktitle="2024 47th International Conference on Telecommunications and Signal Processing (TSP)",
  year="2024",
  pages="270--273",
  publisher="IEEE",
  doi="10.1109/TSP63128.2024.10605914",
  isbn="979-8-3503-6559-7",
  url="https://doi.org/10.1109/TSP63128.2024.10605914"
}