Publication detail

Visualizing Horizontal Gene Transfer Detection in Phylogenetically Divergent Bacteria

SCHWARZEROVÁ, J. RAJASEKARAN, L. JUREČKOVÁ, K. NEJEZCHLEBOVÁ, J. VARGA, M. PROVAZNÍK, V. WECKWERTH, W. ČEJKOVÁ, D.

Original Title

Visualizing Horizontal Gene Transfer Detection in Phylogenetically Divergent Bacteria

Type

conference paper

Language

English

Original Abstract

Horizontal Gene Transfer (HGT) plays an important and indispensable role in the evolution of bacterial genomes, serving as a mechanism that contributes to genetic diversity and enables adaptation across phylogenetically distant taxa. This study introduces an analysis tool implemented as an R package for detecting HGT events in diverse bacterial lineages. The tool combines the integration of a heat-map matrix with phylogenetic analysis visualization techniques to enhance the accuracy and efficiency of HGT event detection. We applied it to a diverse set of bacterial genomes from chicken and pig gut and expanded the results with established methods for HGT detection. The findings demonstrate the capability of our visualization techniques to pinpoint HGT events, offering a valuable tool for researchers to explore the intricate dynamics of bacterial genome evolution.

Keywords

Mobilome; Bioinformatics Data Visualization; Interspecies Gene Transfer; Advanced Comparative Phylogenetics

Authors

SCHWARZEROVÁ, J.; RAJASEKARAN, L.; JUREČKOVÁ, K.; NEJEZCHLEBOVÁ, J.; VARGA, M.; PROVAZNÍK, V.; WECKWERTH, W.; ČEJKOVÁ, D.

Released

28. 8. 2024

Publisher

Springer Nature

ISBN

978-3-031-64636-2

Book

Lecture Notes in Bioinformatics

Edition

14849

Edition number

II.

ISBN

1611-3349

Periodical

Lecture Notes in Computer Science

Year of study

14849

Number

II.

State

Republic of Italy

Pages from

267

Pages to

277

Pages count

11

URL

https://link.springer.com/chapter/10.1007/978-3-031-64636-2_20

BibTex

@inproceedings{BUT189428,
  author="Jana {Schwarzerová} and Laxmipriya {Rajasekaran} and Kateřina {Šabatová} and Julie {Nejezchlebová} and Margaret {Varga} and Valentine {Provazník} and Wolfram {Weckwerth} and Darina {Čejková}",
  title="Visualizing Horizontal Gene Transfer Detection in Phylogenetically Divergent Bacteria",
  booktitle="Lecture Notes in Bioinformatics",
  year="2024",
  series="14849",
  journal="Lecture Notes in Computer Science",
  volume="14849",
  number="II.",
  pages="267--277",
  publisher="Springer Nature",
  doi="10.1007/978-3-031-64636-2\{_}20",
  isbn="978-3-031-64636-2",
  issn="1611-3349",
  url="https://link.springer.com/chapter/10.1007/978-3-031-64636-2_20"
}