Publication detail

Two faces of the antimicrobial peptides and their relevance to burn wound infection

Vána, V. Lipovy, B. Vacek, L. Pavelka, A. Janda, L. Holoubek, J.

Original Title

Two faces of the antimicrobial peptides and their relevance to burn wound infection

Type

journal article in Web of Science

Language

English

Original Abstract

Despite to several modern biomaterials with antimicrobial capacity implemented to wound healing, burn wound infection remains still the most frequent complications within the therapy of these patients. Effectively managing infection not only in the burn wounds is crucial for the successful treatment of patients with burn injuries. Contemporary clinical approaches focused on prompted antibiotic treatment, are facing growing challenges with the increasing resistance exhibited by numerous pathogens. Infections resulting from multi-drug resistant pathogens are recognized to be linked with markedly higher mortality rates compared to those caused by sensitive strains. This underscores the potential of antimicrobial peptides to emerge as future alternative therapeutic modules, offering innovative solutions in the face of limitations encountered by well-established methods

Keywords

Antimicrobial peptides; Immunomodulation; Burn wounds; Cathelicidins

Authors

Vána, V.; Lipovy, B.; Vacek, L.; Pavelka, A.; Janda, L.; Holoubek, J.

Released

1. 9. 2024

Publisher

ELSEVIER SCI LTD

Location

London

ISBN

1879-1409

Periodical

BURNS

Year of study

50

Number

7

State

United Kingdom of Great Britain and Northern Ireland

Pages from

1938

Pages to

1940

Pages count

3

URL

https://www.sciencedirect.com/science/article/pii/S0305417924001554?via%3Dihub

BibTex

@article{BUT189717,
  author="Břetislav {Lipový} and Vladimír {Váňa} and Lukáš {Vacek} and Antonín {Pavelka} and Lubomír {Janda} and Jakub {Holoubek}",
  title="Two faces of the antimicrobial peptides and their relevance to burn wound infection",
  journal="BURNS",
  year="2024",
  volume="50",
  number="7",
  pages="1938--1940",
  doi="10.1016/j.burns.2024.05.014",
  issn="1879-1409",
  url="https://www.sciencedirect.com/science/article/pii/S0305417924001554?via%3Dihub"
}