Publication detail

ECG Segment Variability During Voltage Sensitive Dye Application in Animal Heart

BARDOŇOVÁ, J. VYKLICKÝ, M. PROVAZNÍK, I. NOVÁKOVÁ, M.

Original Title

ECG Segment Variability During Voltage Sensitive Dye Application in Animal Heart

Type

journal article - other

Language

English

Original Abstract

The optical mapping of action potentials from heart surface is extensively used as a new possibility of non-invasive recording methods. It employs application of voltage-sensitive dyes (VSDs). Previously, VSDs has been successfully used in myocardial ischemia studies. Our previous Langendorff perfused heart experiments that have suggested shape changes in ECG signals in time and time-frequency domain caused by application of VSD di-4-ANEPPS during optical mapping. These changes went through detailed analysis to reveal impact to particular fractions of a heart cycle. The heart cycle was divided into three parts, corresponded to P-Q segments, QRS complexes, and ST-T segments. Dynamic time warping (DTW) is applied to all marked segments in each experimental period (control, loading and washout phase). Variability of ECG parts is measured by means of an optimal path resulting from DTW based on minimum distance between the control signal segments (before the application of VSD) and segments recorded in next two experimental steps.

Keywords

Voltage-sensitive dye di-4-ANEPPS, ECG signal, Wavelet analysis, Dynamic Time Warping

Authors

BARDOŇOVÁ, J.; VYKLICKÝ, M.; PROVAZNÍK, I.; NOVÁKOVÁ, M.

RIV year

2005

Released

23. 12. 2005

ISBN

1211-3395

Periodical

Scripta medica

Year of study

78

Number

6

State

Czech Republic

Pages from

273

Pages to

279

Pages count

8

BibTex

@article{BUT46327,
  author="Jana {Kolářová} and Marek {Vyklický} and Valentine {Provazník} and Marie {Nováková}",
  title="ECG Segment Variability During Voltage Sensitive Dye Application in Animal Heart",
  journal="Scripta medica",
  year="2005",
  volume="78",
  number="6",
  pages="273--279",
  issn="1211-3395"
}