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ZÍTKA, O. ŠKUTKOVÁ, H. ADAM, V. TRNKOVÁ, L. BABULA, P. HUBÁLEK, J. PROVAZNÍK, I. KIZEK, R.
Original Title
A New Approach how to Define the Coefficient of Electroactivity of Adenine and Its Twelve Derivatives Using Flow Injection Analysis with Amperometric Detection
Type
journal article in Web of Science
Language
English
Original Abstract
We studied the electrochemical behaviour of adenine derivates (adenosine, 2 - aminopurine, 2,6 - diaminopurine,6 - benzyl - aminopurine, adenosine - monophosphate, cyclic adenosine monophosphate, nicotin amide adenine dinucleotide, adenosine - triphosphate, S-adenosyl - l - methionine and synthetic derivatives AD -3, AD - 6 and AD-9) using flow injection analysis with electrochemical detection. The influences of pH, flow rate and potential on the signal height of the studied derivates were tested. The optimal pH was 3, the flow rate of the mobile phase 0.75 mL min 1 and the potential 1100 mV. Further, we attempted to characterize each of the studied derivatives by mathematical equations and classic analytical parameters.The lowest detecti on limit was estimated for adenine as 0.9 nM and 2 - amino - purine as 0.5nM
Keywords
Adenine derivatives, Flow injection analysis, Amperometric detection, Glassy carbon electrode, Electroactivity
Authors
ZÍTKA, O.; ŠKUTKOVÁ, H.; ADAM, V.; TRNKOVÁ, L.; BABULA, P.; HUBÁLEK, J.; PROVAZNÍK, I.; KIZEK, R.
RIV year
2011
Released
21. 6. 2011
Publisher
WILEY
Location
Weinheim
ISBN
1040-0397
Periodical
ELECTROANALYSIS
Year of study
23
Number
7
State
Federal Republic of Germany
Pages from
1556
Pages to
1567
Pages count
12
BibTex
@article{BUT50938, author="Ondřej {Zítka} and Helena {Vítková} and Vojtěch {Adam} and Libuše {Trnková} and Petr {Babula} and Jaromír {Hubálek} and Valentine {Provazník} and René {Kizek}", title="A New Approach how to Define the Coefficient of Electroactivity of Adenine and Its Twelve Derivatives Using Flow Injection Analysis with Amperometric Detection", journal="ELECTROANALYSIS", year="2011", volume="23", number="7", pages="1556--1567", doi="10.1002/elan.201100064", issn="1040-0397" }