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HYNEK, D. KREJČOVÁ, L. ZÍTKA, O. ADAM, V. TRNKOVÁ, L. SOCHOR, J. STIBOROVÁ, M. ECKSCHLAGER, T. HUBÁLEK, J. KIZEK, R.
Original Title
Electrochemical study of doxorubicin interaction with different sequences of single stranded oligonucleotides, Part I
Type
journal article in Web of Science
Language
English
Original Abstract
Doxorubicin is a know anticancer drug intercalating into dsDNA. The mechanism of interaction of doxorubicin with ssDNA is not clear. In this study adsorptive trřnsfer stripping technique coupled with square wave voltammetry was used for studying of interaction of doxorubicin with single stranded oligonucleotides (ssODN) in various ratios (1:1; 1:2 and 1:5) and interactions times (0-300 min.).
Keywords
intercalating drug; doxorubicin; hetero-nucleotides; square wave voltammetry; adsorptive transfer stripping technique; DNA
Authors
HYNEK, D.; KREJČOVÁ, L.; ZÍTKA, O.; ADAM, V.; TRNKOVÁ, L.; SOCHOR, J.; STIBOROVÁ, M.; ECKSCHLAGER, T.; HUBÁLEK, J.; KIZEK, R.
RIV year
2012
Released
1. 1. 2012
ISBN
1452-3981
Periodical
INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE
Year of study
7
Number
1
State
Republic of Serbia
Pages from
13
Pages to
33
Pages count
21
BibTex
@article{BUT75710, author="HYNEK, D. and KREJČOVÁ, L. and ZÍTKA, O. and ADAM, V. and TRNKOVÁ, L. and SOCHOR, J. and STIBOROVÁ, M. and ECKSCHLAGER, T. and HUBÁLEK, J. and KIZEK, R.", title="Electrochemical study of doxorubicin interaction with different sequences of single stranded oligonucleotides, Part I", journal="INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE", year="2012", volume="7", number="1", pages="13--33", issn="1452-3981" }