Publication detail

Electrochemical study of doxorubicin interaction with different sequences of single stranded oligonucleotides, Part I

HYNEK, D. KREJČOVÁ, L. ZÍTKA, O. ADAM, V. TRNKOVÁ, L. SOCHOR, J. STIBOROVÁ, M. ECKSCHLAGER, T. HUBÁLEK, J. KIZEK, R.

Original Title

Electrochemical study of doxorubicin interaction with different sequences of single stranded oligonucleotides, Part I

Type

journal article in Web of Science

Language

English

Original Abstract

Doxorubicin is a know anticancer drug intercalating into dsDNA. The mechanism of interaction of doxorubicin with ssDNA is not clear. In this study adsorptive trřnsfer stripping technique coupled with square wave voltammetry was used for studying of interaction of doxorubicin with single stranded oligonucleotides (ssODN) in various ratios (1:1; 1:2 and 1:5) and interactions times (0-300 min.).

Keywords

intercalating drug; doxorubicin; hetero-nucleotides; square wave voltammetry; adsorptive transfer stripping technique; DNA

Authors

HYNEK, D.; KREJČOVÁ, L.; ZÍTKA, O.; ADAM, V.; TRNKOVÁ, L.; SOCHOR, J.; STIBOROVÁ, M.; ECKSCHLAGER, T.; HUBÁLEK, J.; KIZEK, R.

RIV year

2012

Released

1. 1. 2012

ISBN

1452-3981

Periodical

INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE

Year of study

7

Number

1

State

Republic of Serbia

Pages from

13

Pages to

33

Pages count

21

BibTex

@article{BUT75710,
  author="HYNEK, D. and KREJČOVÁ, L. and ZÍTKA, O. and ADAM, V. and TRNKOVÁ, L. and SOCHOR, J. and STIBOROVÁ, M. and ECKSCHLAGER, T. and HUBÁLEK, J. and KIZEK, R.",
  title="Electrochemical study of doxorubicin interaction with different sequences of single stranded oligonucleotides, Part I",
  journal="INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE",
  year="2012",
  volume="7",
  number="1",
  pages="13--33",
  issn="1452-3981"
}