Přístupnostní navigace
E-application
Search Search Close
Publication detail
LÍZAL, F. ELCNER, J. HOPKE, P. JEDELSKÝ, J. JÍCHA, M.
Original Title
Development of a realistic human airway model
Type
journal article in Web of Science
Language
English
Original Abstract
Numerous models of human lungs with various levels of idealization have been reported in the literature; consequently, results acquired using these models are difficult to compare to in vivo measurements. We have developed a set of model components based on realistic geometries, which permits the analysis of the effects of subsequent model simplification. A realistic digital upper airway geometry except for the lack of an oral cavity has been created which proved suitable both for computational fluid dynamics (CFD) simulations and for the fabrication of physical models. Subsequently, an oral cavity was added to the tracheobronchial geometry. The airway geometry including the oral cavity was adjusted to enable fabrication of a semi-realistic model. Five physical models were created based on these three digital geometries. Two optically transparent models, one with and one without the oral cavity, were constructed for flow velocity measurements, two realistic segmented models, one with and one without the oral cavity, were constructed for particle deposition measurements, and a semi-realistic model with glass cylindrical airways was developed for optical measurements of flow velocity and in situ particle size measurements. One-dimensional phase doppler anemometry measurements were made and compared to the CFD calculations for this model and good agreement was obtained.
Keywords
Human airway model, tracheo-bronchial tree, particle transport, particle deposition, oral cavity
Authors
LÍZAL, F.; ELCNER, J.; HOPKE, P.; JEDELSKÝ, J.; JÍCHA, M.
RIV year
2012
Released
17. 2. 2012
Publisher
SAGE PUBLICATIONS LTD
Location
London
ISBN
0954-4119
Periodical
PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE
Year of study
226
Number
H3
State
United Kingdom of Great Britain and Northern Ireland
Pages from
197
Pages to
207
Pages count
11
URL
http://pih.sagepub.com/content/early/2011/12/02/0954411911430188
BibTex
@article{BUT76135, author="František {Lízal} and Jakub {Elcner} and Philip K. {Hopke} and Jan {Jedelský} and Miroslav {Jícha}", title="Development of a realistic human airway model", journal="PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE", year="2012", volume="226", number="H3", pages="197--207", issn="0954-4119", url="http://pih.sagepub.com/content/early/2011/12/02/0954411911430188" }