Publication detail

DNA-doxorubicin interactions revealed by electrochemistry

MASAŘIK,M. KYNCLOVA,H. HÚSKA,D. HUBÁLEK,J. ADAM,V., BABULA,P. ECKSCHLAGER,T. STIBOROVÁ,M., KIZEK,R.

Original Title

DNA-doxorubicin interactions revealed by electrochemistry

Type

abstract

Language

English

Original Abstract

Anthracyclines including doxorubicin are commonly used in the treatment of a number of diverse malignant tumours - acute leukaemia, non-Hodgkin and Hodgkin lymphoma and several solid tumours including neuroblastoma. The aim of this study was to compare effects of doxorubicin on sensitive and resistant cells by using electrochemical and mathematical methods. We compared differences between signals of DNA isolated from sensitive and resistant tumour cells by statistical models.

Keywords

doxorubicin, Anthracyclines

Authors

MASAŘIK,M.; KYNCLOVA,H.; HÚSKA,D.; HUBÁLEK,J.; ADAM,V., BABULA,P.; ECKSCHLAGER,T.; STIBOROVÁ,M., KIZEK,R.

Released

1. 1. 2010

Publisher

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

ISBN

1107-3756

Periodical

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Year of study

26

Number

1

State

United States of America

Pages from

S46

Pages to

S46

Pages count

1