Publication detail

Novel Electrochemical Biosensor for Simultaneous Detection of Adenine and Guanine Based on Cu2O Nanoparticles

CHOMOUCKÁ, J. PRÁŠEK, J. BUŠINOVÁ, P. TRNKOVÁ, L. DRBOHLAVOVÁ, J. PEKÁREK, J. HRDÝ, R. HUBÁLEK, J.

Original Title

Novel Electrochemical Biosensor for Simultaneous Detection of Adenine and Guanine Based on Cu2O Nanoparticles

Type

journal article in Web of Science

Language

English

Original Abstract

In this paper Cu2O nanoparticles were prepared and used for the construction of novel electrochemical voltammetric biosensor for the simultaneous detection of adenine and guanine. Cu2O nanoparticles were synthesized via simple wet chemical route, where glucose was used as a reductant. The nanoparticles were characterized by SEM and XRD analysis, which showed the presence of spherical aggregations with diameter of 1000 nm. These nanoparticles were successfully used for fabrication of spray-coated and screen-printed working electrodes on alumina substrate for the electrochemical detection of purine bases. We observed that Cu(I) reacts with adenine to form insoluble complex that accumulates on the electrode surface and causes the decrease of current response. In the case of guanine, we did not observed any significant decrease of current response which is probably caused by adsorption of guanine on the electrode surface.

Keywords

Thick film technology, electrochemistry, cyclic voltametry, copper(I) oxide, purines

Authors

CHOMOUCKÁ, J.; PRÁŠEK, J.; BUŠINOVÁ, P.; TRNKOVÁ, L.; DRBOHLAVOVÁ, J.; PEKÁREK, J.; HRDÝ, R.; HUBÁLEK, J.

RIV year

2012

Released

2. 11. 2012

Publisher

Elsevier

Location

Krakow, Poland

ISBN

1877-7058

Periodical

Procedia Engineering

Year of study

47

Number

11

State

Kingdom of the Netherlands

Pages from

702

Pages to

705

Pages count

4

URL

https://www.sciencedirect.com/science/article/pii/S187770581204307X

Full text in the Digital Library

http://hdl.handle.net/11012/193508

BibTex

@article{BUT94718,
  author="Jana {Pekárková} and Jan {Prášek} and Petra {Majzlíková} and Libuše {Trnková} and Jana {Drbohlavová} and Jan {Pekárek} and Radim {Hrdý} and Jaromír {Hubálek}",
  title="Novel Electrochemical Biosensor for Simultaneous Detection of Adenine and Guanine Based on Cu2O Nanoparticles",
  journal="Procedia Engineering",
  year="2012",
  volume="47",
  number="11",
  pages="702--705",
  doi="10.1016/j.proeng.2012.09.244",
  issn="1877-7058",
  url="https://www.sciencedirect.com/science/article/pii/S187770581204307X"
}