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CHOMOUCKÁ, J. PRÁŠEK, J. MAJZLÍKOVÁ, P. TRNKOVÁ, L. DRBOHLAVOVÁ, J. PEKÁREK, J. HRDÝ, R. HUBÁLEK, J.
Original Title
Simultaneous Detection of Purine Bases on Cu2O Nanoparticles Based Electrochemical Biosensor
Type
conference paper
Language
English
Original Abstract
Electrochemical determination of purine bases using screen-printed and spray-coated working electrodes on alumina substrate based on Cu2O nanoparticles is described in this work. Cu2O nanoparticles were synthetized using simple precipitation method and used for thick-film planar microelectrodes fabrication. The Cu2O nanoparticles were characterized by SEM and XRD analysis, which showed the presence of spherical aggregations with diameter of 1000 nm. Fabricated working electrodes based on these Cu2O nanoparticles were successfully used for adenine and guanine determination. The purine bases were detected indirectly by reduction of Cu ions. The current response of both electrodes types decreased with increasing adenine or guanine concentration. More sensitive detection was achieved with spray-coated electrodes with higher active surface area.
Keywords
thick film technology, cyclic voltametry, electrochemistry, copper oxide, purine bases, DNA
Authors
CHOMOUCKÁ, J.; PRÁŠEK, J.; MAJZLÍKOVÁ, P.; TRNKOVÁ, L.; DRBOHLAVOVÁ, J.; PEKÁREK, J.; HRDÝ, R.; HUBÁLEK, J.
RIV year
2012
Released
28. 10. 2012
Publisher
IEEE
Location
345 E 47TH ST, NEW YORK, NY 10017 USA
ISBN
978-1-4577-1765-9
Book
Proceedings of IEEE Sensors 2012
Pages from
1
Pages to
4
Pages count
BibTex
@inproceedings{BUT96041, author="Jana {Pekárková} and Jan {Prášek} and Petra {Majzlíková} and Libuše {Trnková} and Jana {Drbohlavová} and Jan {Pekárek} and Radim {Hrdý} and Jaromír {Hubálek}", title="Simultaneous Detection of Purine Bases on Cu2O Nanoparticles Based Electrochemical Biosensor", booktitle="Proceedings of IEEE Sensors 2012", year="2012", pages="1--4", publisher="IEEE", address="345 E 47TH ST, NEW YORK, NY 10017 USA", isbn="978-1-4577-1765-9" }