Publication detail

Simultaneous Detection of Purine Bases on Cu2O Nanoparticles Based Electrochemical Biosensor

CHOMOUCKÁ, J. PRÁŠEK, J. MAJZLÍKOVÁ, P. TRNKOVÁ, L. DRBOHLAVOVÁ, J. PEKÁREK, J. HRDÝ, R. HUBÁLEK, J.

Original Title

Simultaneous Detection of Purine Bases on Cu2O Nanoparticles Based Electrochemical Biosensor

Type

conference paper

Language

English

Original Abstract

Electrochemical determination of purine bases using screen-printed and spray-coated working electrodes on alumina substrate based on Cu2O nanoparticles is described in this work. Cu2O nanoparticles were synthetized using simple precipitation method and used for thick-film planar microelectrodes fabrication. The Cu2O nanoparticles were characterized by SEM and XRD analysis, which showed the presence of spherical aggregations with diameter of 1000 nm. Fabricated working electrodes based on these Cu2O nanoparticles were successfully used for adenine and guanine determination. The purine bases were detected indirectly by reduction of Cu ions. The current response of both electrodes types decreased with increasing adenine or guanine concentration. More sensitive detection was achieved with spray-coated electrodes with higher active surface area.

Keywords

thick film technology, cyclic voltametry, electrochemistry, copper oxide, purine bases, DNA

Authors

CHOMOUCKÁ, J.; PRÁŠEK, J.; MAJZLÍKOVÁ, P.; TRNKOVÁ, L.; DRBOHLAVOVÁ, J.; PEKÁREK, J.; HRDÝ, R.; HUBÁLEK, J.

RIV year

2012

Released

28. 10. 2012

Publisher

IEEE

Location

345 E 47TH ST, NEW YORK, NY 10017 USA

ISBN

978-1-4577-1765-9

Book

Proceedings of IEEE Sensors 2012

Pages from

1

Pages to

4

Pages count

4

BibTex

@inproceedings{BUT96041,
  author="Jana {Pekárková} and Jan {Prášek} and Petra {Majzlíková} and Libuše {Trnková} and Jana {Drbohlavová} and Jan {Pekárek} and Radim {Hrdý} and Jaromír {Hubálek}",
  title="Simultaneous Detection of Purine Bases on Cu2O Nanoparticles Based Electrochemical Biosensor",
  booktitle="Proceedings of IEEE Sensors 2012",
  year="2012",
  pages="1--4",
  publisher="IEEE",
  address="345 E 47TH ST, NEW YORK, NY 10017 USA",
  isbn="978-1-4577-1765-9"
}