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LÍZAL, F. ELCNER, J. BĚLKA, M. JEDELSKÝ, J. HOPKE, P. ŠTARHA, P. DRUCKMÜLLEROVÁ, H. JÍCHA, M.
Original Title
Measurement of Fiber Deposition in a Human Lung Model by Phase Contrast Microscopy with Automated Image Analysis
Type
journal article - other
Language
English
Original Abstract
Deposition of fibers in human lungs is known as a health hazard. In-vitro measurements were performed with monodisperse glass fibers in a realistic model of human lungs up to seventh generation of branching to estimate the effect of fiber size and breathing pattern on fiber deposition. Deposited fibers were rinsed from the model segments and gathered on nitrocellulose filters. Phase-contrast microscopy with high resolution camera was used to capture images of filters with fibers. New software was developed for an automated image analysis and local deposition characteristics were calculated afterwards. The whole method proved to be a useful and valuable tool for the evaluation of fiber and particle deposition.
Keywords
Human Lungs, Deposition, Fibers, Image analysis
Authors
LÍZAL, F.; ELCNER, J.; BĚLKA, M.; JEDELSKÝ, J.; HOPKE, P.; ŠTARHA, P.; DRUCKMÜLLEROVÁ, H.; JÍCHA, M.
RIV year
2013
Released
20. 12. 2013
Publisher
Association for Engineering Mechanics
Location
Brno
ISBN
1802-1484
Periodical
Engineering Mechanics
Year of study
20
Number
3/4
State
Czech Republic
Pages from
187
Pages to
194
Pages count
8
BibTex
@article{BUT96300, author="František {Lízal} and Jakub {Elcner} and Miloslav {Bělka} and Jan {Jedelský} and Philip K. {Hopke} and Pavel {Štarha} and Hana {Druckmüllerová} and Miroslav {Jícha}", title="Measurement of Fiber Deposition in a Human Lung Model by Phase Contrast Microscopy with Automated Image Analysis", journal="Engineering Mechanics", year="2013", volume="20", number="3/4", pages="187--194", issn="1802-1484" }