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POHANKA, M. FUSEK, J. ADAM, V. KIZEK, R.
Original Title
Carbofuran assay using Gelatin based Biosensor with Acetylcholinesterase as a Recognition Element
Type
journal article in Web of Science
Language
English
Original Abstract
Carbofuran is a neurotoxic pesticide acting as an inhibitor of enzyme acetylcholinesterase (AChE). The fact that carbofuran is able to inhibit AChE can be used for its assay using an appropriate sensor. AChE was immobilized into gelatin membrane. The immobilization procedure was optimized considering temperature of drying and concentration of gelatin in mixture. Long term stability and interference of organic solvent was done as well. In the final experiment, carbofuran was assayed using the prepared biosensor. Limit of detection 5.01 10-10 mol/l (0.111 ng/ml) was achieved.
Keywords
biosensor; acetylcholinesterase; pesticide; inhibitor; screen printed electrode; voltammetry; amperometry
Authors
POHANKA, M.; FUSEK, J.; ADAM, V.; KIZEK, R.
RIV year
2013
Released
1. 1. 2013
ISBN
1452-3981
Periodical
INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE
Year of study
8
Number
1
State
Republic of Serbia
Pages from
71
Pages to
79
Pages count
9
BibTex
@article{BUT98896, author="Miroslav {Pohanka} and Josef {Fusek} and Vojtěch {Adam} and René {Kizek}", title="Carbofuran assay using Gelatin based Biosensor with Acetylcholinesterase as a Recognition Element", journal="INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE", year="2013", volume="8", number="1", pages="71--79", issn="1452-3981" }