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ŘEHÁK, K. SKALLERUD, B.
Original Title
Micro-CT Based Imaging and Numerical Analysis of Bone Healing
Type
conference paper
Language
English
Original Abstract
During distraction osteogenesis (bone lengthening) one phase is lengthening and a second phase is consolidation (fixed length, bone maturation). In this second phase of fracture healing, the callus consists of several tissue types. The response of callus bone to mechanical loading can determine the progress of treatment. The mechanical strain distribution could provide additional information of fracture healing in the same way as for bone remodeling. The architecture and tissue properties significantly affect the strength of the whole callus bone. This article focuses on imaging and numerical analysis of bone fracture healing based on input information obtained from micro-CT scans. The objective of this study is to focus on how different stiffness threshold values affect the load carrying tissue architecture and how this further influences the strain distributions within the callus. Finite element simulations are employed to investigate this. A rabbit tibia fracture callus was micro-CT scanned 30 days after osteotomy using an isotropic voxel size of 0.000020 mm. Four computational models were created with different pixel threshold values to cover a wide range of callus tissue properties, with the purpose of finding an optimal threshold value. Optimal means here a finite element model which is computationally feasible and still contains the main load carrying tissue. The values of bone volume/total callus volume (BV/TV), bone area/total callus area (BA/TA), trabecular thickness, structure model index (SMI) were quantified to compare the differences between models. All finite element models were axially loaded to investigate the influence of threshold value on the callus reaction and influence of including the soft tissue. The BV/TV and BA/TA values indicate that for a certain threshold level, finite element models are suitable. However, a too high threshold leads to invalid finite element models. The finite element method (FEM) could be useful tool in understanding of fracture healing process.
Keywords
micro-CT, fracture callus, microstructure, tissue properties, finite element method.
Authors
ŘEHÁK, K.; SKALLERUD, B.
RIV year
2014
Released
24. 3. 2014
Publisher
Trans Tech Publications
Location
Switzerland
ISBN
978-3-03835-062-0
Book
Local Mechanical Properties X
1013-9826
Periodical
Key Engineering Materials (print)
Year of study
Number
606
State
Swiss Confederation
Pages from
141
Pages to
144
Pages count
4
BibTex
@inproceedings{BUT107629, author="Kamil {Řehák} and Bjorn {Skallerud}", title="Micro-CT Based Imaging and Numerical Analysis of Bone Healing", booktitle="Local Mechanical Properties X", year="2014", journal="Key Engineering Materials (print)", volume="2014", number="606", pages="141--144", publisher="Trans Tech Publications", address="Switzerland", doi="10.4028/http://www.scientific.net/KEM.606.141", isbn="978-3-03835-062-0", issn="1013-9826" }