Publication detail

Facile method of building hydroxyapatite 3D scaffolds assembled from porous hollow fibers enabling nutrient delivery

SALAMON, D. TEIXEIRA, S. DUTCZAK, S. STAMATIALIS, D.

Original Title

Facile method of building hydroxyapatite 3D scaffolds assembled from porous hollow fibers enabling nutrient delivery

Type

journal article in Web of Science

Language

English

Original Abstract

Nowadays, diffusion through scaffold and tissue usually limits transport, and forms potentially hypoxic regions. Several methods are used for preparation of 3D hydroxyapatite scaffolds, however, production of a scaffold including porous hollow fibers for nutrition delivery is difficult and expensive. In this study, we describe an easy and inexpensive method to create 3D hydroxyapatite structure containing porous hollow fibers via microtemplating. The fibers which are assembled into 3D scaffold and sintered, contain asymmetric membrane walls with flux suitable for nutrient delivery. These hollow fibers have good mesenchymal stem cell adhesion showing that the presented method has no negative influence on cell cytocompatibility. The proposed straightforward method for building 3D structures containing porous hollow fibers for nutritions can be suitable for in vitro bioreactors studies as well as for production tissue engineered or in vivo prepared bone grafts.

Keywords

Sintering; Membrane; Hydroxyapatite; Microtemplating; Cell adhesion

Authors

SALAMON, D.; TEIXEIRA, S.; DUTCZAK, S.; STAMATIALIS, D.

RIV year

2014

Released

30. 6. 2014

ISBN

0272-8842

Periodical

Ceramics International

Year of study

40

Number

9

State

United Kingdom of Great Britain and Northern Ireland

Pages from

14793

Pages to

14799

Pages count

6

BibTex

@article{BUT110617,
  author="David {Salamon} and Sandra {Teixeira} and Szymon M. {Dutczak} and Dimitrios F. {Stamatialis}",
  title="Facile method of building hydroxyapatite 3D scaffolds assembled from porous hollow fibers enabling nutrient delivery",
  journal="Ceramics International",
  year="2014",
  volume="40",
  number="9",
  pages="14793--14799",
  doi="10.1016/j.ceramint.2014.06.071",
  issn="0272-8842"
}