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HEGER, Z. ZÍTKA, O. FOHLEROVÁ, Z. MERLOS RODRIGO, M. HUBÁLEK, J. KIZEK, R. ADAM, V.
Original Title
Use of green fluorescent proteins for in vitro biosensing.
Type
journal article in Web of Science
Language
English
Original Abstract
Due to the considerable stability of green fluorescent proteins and their capacity to be readily permutated or mutated, they may be exploited in multiple ways to enhance the functionality of in vitro biosensors. Many possibilities, such as the formation of chimeras with other proteins or antibodies, as well as Förster resonance emission transfer performance, may be used for the highly sensitive and specific detection of the target molecules. This review considers the great potential of green fluorescent proteins as the fluorescent probing or recognition biomolecule in various in vitro biosensors applications, as well as obstacles associated with their use.
Keywords
Aequorea victoria; biosensor; chimera; emission; Förster resonance emission transfer
Authors
HEGER, Z.; ZÍTKA, O.; FOHLEROVÁ, Z.; MERLOS RODRIGO, M.; HUBÁLEK, J.; KIZEK, R.; ADAM, V.
RIV year
2015
Released
1. 1. 2015
Publisher
Chemical Papers
ISBN
0366-6352
Periodical
Year of study
69
Number
1
State
Slovak Republic
Pages from
54
Pages to
61
Pages count
8
BibTex
@article{BUT112066, author="Zbyněk {Heger} and Ondřej {Zítka} and Zdenka {Fohlerová} and Miguel Ángel {Merlos Rodrigo} and Jaromír {Hubálek} and René {Kizek} and Vojtěch {Adam}", title="Use of green fluorescent proteins for in vitro biosensing.", journal="Chemical Papers", year="2015", volume="69", number="1", pages="54--61", doi="10.2478/s11696-014-0588-9", issn="0366-6352" }