Publication detail

Assessing progress of Parkinson's disease using acoustic analysis of phonation

MEKYSKA, J. GALÁŽ, Z. MŽOUREK, Z. SMÉKAL, Z. REKTOROVÁ, I. ELIÁŠOVÁ, I. KOŠŤÁLOVÁ, M. MRAČKOVÁ, M. BERANKOVA, D. FAÚNDEZ ZANUY, M. LOPEZ-DE-IPINA, K. ALONSO-HERNANDEZ, J.

Original Title

Assessing progress of Parkinson's disease using acoustic analysis of phonation

Type

conference paper

Language

English

Original Abstract

This paper deals with a complex acoustic analysis of phonation in patients with Parkinson's disease (PD) with a special focus on estimation of disease progress that is described by 7 different clinical scales (e. g. Unified Parkinson's disease rating scale or Beck depression inventory). The analysis is based on parametrization of 5 Czech vowels pronounced by 84 PD patients. Using classification and regression trees we estimated all clinical scores with maximal error lower or equal to 13 %. Best estimation was observed in the case of Mini-mental state examination (MAE = 0.77, estimation error 5.50 %). Finally, we proposed a binary classification based on random forests that is able to identify Parkinson's disease with sensitivity SEN = 92.86% (SPE = 85.71 %). The parametrization process was based on extraction of 107 speech features quantifying different clinical signs of hypokinetic dysarthria present in PD.

Keywords

Parkinson’s disease, hypokinetic dysarthria, speech analysis, clinical scores

Authors

MEKYSKA, J.; GALÁŽ, Z.; MŽOUREK, Z.; SMÉKAL, Z.; REKTOROVÁ, I.; ELIÁŠOVÁ, I.; KOŠŤÁLOVÁ, M.; MRAČKOVÁ, M.; BERANKOVA, D.; FAÚNDEZ ZANUY, M.; LOPEZ-DE-IPINA, K.; ALONSO-HERNANDEZ, J.

RIV year

2015

Released

10. 6. 2015

ISBN

978-1-4673-7845-1

Book

2015 4th International Work Conference on Bioinspired Intelligence (IWOBI)

Pages from

111

Pages to

118

Pages count

8

URL

https://ieeexplore.ieee.org/document/7160153?reload=true&arnumber=7160153

BibTex

@inproceedings{BUT115864,
  author="Jiří {Mekyska} and Zoltán {Galáž} and Zdeněk {Mžourek} and Zdeněk {Smékal} and Irena {Rektorová} and Ilona {Eliášová} and Milena {Košťálová} and Martina {Mračková} and Dagmar {Berankova} and Marcos {Faúndez Zanuy} and Karmele {Lopez-de-Ipina} and Jesus {Alonso-Hernandez}",
  title="Assessing progress of Parkinson's disease using acoustic analysis of phonation",
  booktitle="2015 4th International Work Conference on Bioinspired Intelligence (IWOBI)",
  year="2015",
  pages="111--118",
  doi="10.1109/IWOBI.2015.7160153",
  isbn="978-1-4673-7845-1",
  url="https://ieeexplore.ieee.org/document/7160153?reload=true&arnumber=7160153"
}