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PEŠL, M. PŘIBYL, J. ČMIEL, V. AĆIMOVIĆ, I. JELÍNKOVÁ, Š. DVOŘÁK, P. STÁREK, Z. SKLÁDAL, P. ROTREKL, V.
Original Title
Phenotypic assays for analysis of pluripotent stem cell derived cardiomyocytes
Type
journal article in Web of Science
Language
English
Original Abstract
A novel approach combining atomic force microscopy, fluorescent microscopy, and external electrophysiology through microelectrode arrays is introduced. The paper demonstrates that this novel method can be used to gain unique information on the complex excitation-contraction coupling dynamics of the hPSC-derived CMs.
Keywords
atomic force microscopy; cardiomyocytes; differentiation; drug screening; drug toxicity; hESC; hiPSC; high-throughput screening
Authors
PEŠL, M.; PŘIBYL, J.; ČMIEL, V.; AĆIMOVIĆ, I.; JELÍNKOVÁ, Š.; DVOŘÁK, P.; STÁREK, Z.; SKLÁDAL, P.; ROTREKL, V.
Released
30. 1. 2017
Publisher
Journal of Molecular Recognition
ISBN
0952-3499
Periodical
JOURNAL OF MOLECULAR RECOGNITION
Year of study
30
Number
6
State
United Kingdom of Great Britain and Northern Ireland
Pages from
1
Pages to
14
Pages count
BibTex
@article{BUT130369, author="Martin {Pešl} and Jan {Přibyl} and Vratislav {Čmiel} and Ivana {Aćimović} and Šárka {Jelínková} and Petr {Dvořák} and Zdeněk {Stárek} and Petr {Skládal} and Vladimír {Rotrekl}", title="Phenotypic assays for analysis of pluripotent stem cell derived cardiomyocytes", journal="JOURNAL OF MOLECULAR RECOGNITION", year="2017", volume="30", number="6", pages="1--14", doi="10.1002/jmr.2602", issn="0952-3499" }