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KUČERA, D. NOVÁČKOVÁ, I. PERNICOVÁ, I. OBRUČA, S.
Original Title
Adaptation of PHA producing bacteria to levulinic acid
Type
conference paper
Language
English
Original Abstract
Polyhydroxyalkanoates (PHAs) are bacterial polyesters which are considered as biodegradable and environmentally-friendly alternative to petrochemical plastics. Poly-3-hydroxybutyrate is typical but in the plastics industry, the copolymer of poly-3-hydroxybutyrate-co-3-hydroxyvalerate (P3HB-co-3HV) is significantly better utilized due to its material properties. The aim was to use the concept of evolutionary engineering to obtain strains capable of utilization levulinic acid for production P3HB-co-3HV. Adaptation tests were carried out with the Cupriavidus necator H16 strain. Higher LA concentrations have been shown to significantly reduce the growth of the selected strain. Adaptation tests led to an increase in the proportion of PHV in the copolymer produced.
Keywords
polyhydroxyalkanoates, stress, levulinic acid, adaptation, evolutionary engineering
Authors
KUČERA, D.; NOVÁČKOVÁ, I.; PERNICOVÁ, I.; OBRUČA, S.
Released
21. 11. 2018
Publisher
Czech Society of Industrial Chemistry
Location
Prague
ISBN
978-80-86238-77-7
Book
Proceedings of the 6th International Conference on Chemical Technology
Edition
1st edition
2336-8128
Periodical
International Conference on Chemical Technology
State
Czech Republic
Pages from
74
Pages to
77
Pages count
4
URL
http://www.icct.cz/AngiologyKlon-ICCT/media/system/2018/ICCT-2018-Proceedings.pdf
BibTex
@inproceedings{BUT151361, author="Dan {Kučera} and Ivana {Nováčková} and Iva {Buchtíková} and Stanislav {Obruča}", title="Adaptation of PHA producing bacteria to levulinic acid", booktitle="Proceedings of the 6th International Conference on Chemical Technology", year="2018", series="1st edition", journal="International Conference on Chemical Technology", pages="74--77", publisher="Czech Society of Industrial Chemistry", address="Prague", isbn="978-80-86238-77-7", issn="2336-8128", url="http://www.icct.cz/AngiologyKlon-ICCT/media/system/2018/ICCT-2018-Proceedings.pdf" }