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KRATOCHVÍLOVÁ, I. ASHCHEULOV, P. KOVALENKO, A. ZÁLIŠ, S. LEDVINA, M. MÍČOVÁ, J.
Original Title
Luminescent Diamond Nanoparticles: Physical, Chemical and Biological Aspects of the Phenomenon (Retracted Article)
Type
journal article in Web of Science
Language
English
Original Abstract
Biosensors based on nanodiamonds are able to penetrate through the cell membrane in a targeted manner and probe changes in real-time in the inner cellular space. In this work we performed exclusive theoretical and experimental study of nanodiamond particles adjusted for application in optically-traceable intracellular nanodiamond sensors. Theoretical and experimental study of specific optical properties of high-pressure high-temperature nanodiamonds containing NV- and NV0 centres were performed. The results are supported by theoretical modeling. The final result of this study was detection of luminescence ND in living cells and in vivo application od luminiscence NDs in chicken embryo, showing the detectability of luminescence ND using a standard confocal microscope. On the level of in cells selectivity numerous clusters of ND particles were present within the cytoplasm and at the same time no particles were absent in the nucleus-ND particles can be used as imaging or delivery system for specific cell parts targeting. From our study we can say that biosensors based on nanodiamonds (NDs) are able to penetrate through the cell membrane in a targeted manner and probe changes in the inner cellular space.
Keywords
Nanodiamonds Luminiscence; NV Centres; In-Cells Imaging; In-Vivo Imaging
Authors
KRATOCHVÍLOVÁ, I.; ASHCHEULOV, P.; KOVALENKO, A.; ZÁLIŠ, S.; LEDVINA, M.; MÍČOVÁ, J.
Released
1. 9. 2015
Publisher
AMER SCIENTIFIC PUBLISHERS
Location
VALENCIA
ISBN
1533-4899
Periodical
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
Year of study
15
Number
2
State
United States of America
Pages from
1000
Pages to
1005
Pages count
6
URL
https://www.ingentaconnect.com/content/asp/jnn/2015/00000015/00000002/art00008;jsessionid=j3cw8b1w9cc2.x-ic-live-03
BibTex
@article{BUT163321, author="Irena {Kratochvílová} and Petr {Ashcheulov} and Alexander {Kovalenko} and Stanislav {Záliš} and Miroslav {Ledvina} and Julia {Míčová}", title="Luminescent Diamond Nanoparticles: Physical, Chemical and Biological Aspects of the Phenomenon (Retracted Article)", journal="JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY", year="2015", volume="15", number="2", pages="1000--1005", doi="10.1166/jnn.2015.9740", issn="1533-4899", url="https://www.ingentaconnect.com/content/asp/jnn/2015/00000015/00000002/art00008;jsessionid=j3cw8b1w9cc2.x-ic-live-03" }