Publication detail

A COMPACT MEMS CHIP FOR A RAPID AND HIGHLY ACCURATE PICOLITER CALORIMETRY

NI, S. ZHU, H. NEUŽIL, P. YOBAS, L.

Original Title

A COMPACT MEMS CHIP FOR A RAPID AND HIGHLY ACCURATE PICOLITER CALORIMETRY

Type

conference paper

Language

English

Original Abstract

We introduce a compact MEMS-based microcalorimeter (mu C) for rapid ultrasmall-volume sample analysis. The chip features a time constant of 4 ms, with the possibility of achieving high scanning rate and sensitivity without noticeably distorting the thermograms. We demonstrated the chip performance in differential scanning calorimeter (DSC) mode and measured the melting temperature (T-m) of bovine serum albumin (BSA) at 75 K.min(-1), one of the fastest scan rate reported. The measured melting point of 77.4 degrees C is practically identical to that measured by a conventional MEMS-based DSC. Our system exhibits an unprecedented accuracy at such a high scanning rate having the capability of perfomring a flash DSC analysis for a liquid phase sample.

Keywords

Microcalorimeter; Picoliter; Self-enclosed Channel; Time Constant; Scanning Rate; Microfluidics

Authors

NI, S.; ZHU, H.; NEUŽIL, P.; YOBAS, L.

Released

6. 4. 2020

Publisher

IEEE

Location

NEW YORK

ISBN

978-1-7281-3581-6

Book

IEEE International Conference on Micro Electro Mechanical Systems

Pages from

1006

Pages to

1009

Pages count

4

URL

https://ieeexplore.ieee.org/abstract/document/9056359?casa_token=0OdaukJW1VwAAAAA:8zS97fQTPSlE6oijiGViP9h-MKMsHSAE65eM-UcQpA1t_VgJxofZe5RkLLlNb8g44WBHkqM0O_M

BibTex

@inproceedings{BUT165707,
  author="NI, S. and ZHU, H. and NEUŽIL, P. and YOBAS, L.",
  title="A COMPACT MEMS CHIP FOR A RAPID AND HIGHLY ACCURATE PICOLITER CALORIMETRY",
  booktitle="IEEE International Conference on Micro Electro Mechanical Systems",
  year="2020",
  pages="1006--1009",
  publisher="IEEE",
  address="NEW YORK",
  doi="10.1109/MEMS46641.2020.9056359",
  isbn="978-1-7281-3581-6",
  url="https://ieeexplore.ieee.org/abstract/document/9056359?casa_token=0OdaukJW1VwAAAAA:8zS97fQTPSlE6oijiGViP9h-MKMsHSAE65eM-UcQpA1t_VgJxofZe5RkLLlNb8g44WBHkqM0O_M"
}