Publication detail

Hysteresis during heating and cooling of hyaluronan solutions in water observed by means of ultrasound velocimetry

JUGL, A. HURČÍKOVÁ, A. PEKAŘ, M.

Original Title

Hysteresis during heating and cooling of hyaluronan solutions in water observed by means of ultrasound velocimetry

Type

journal article in Web of Science

Language

English

Original Abstract

Ultrasound velocity was measured in hyaluronan solutions of various compositions at different temperatures. The velocity dependence on hyaluronan concentration at constant temperature (25 °C) was linear both in water and in 0.15 M NaCl regardless of hyaluronan molecular weight, confirming diluted-solution behavior. During cyclic heating and cooling, hysteresis on the temperature dependence of ultrasound velocity was observed in the range 30–55 °C in aqueous solutions for all molecular weights. In NaCl solutions, the hysteresis was suppressed and, in contrast to solutions in water where the velocity demonstrated a local maximum with temperature, the velocity decreased with increasing temperature. These findings were attributed to slow and hydration-linked hyaluronan conformation transitions during cooling in water, which were suppressed by the presence of salt, which makes hyaluronan's coiled conformation more compact.

Keywords

Hyaluronan; Ultrasound velocimetry; Ultrasonic velocity; Compressibility; Apparent specific compressibility; Hysteresis

Authors

JUGL, A.; HURČÍKOVÁ, A.; PEKAŘ, M.

Released

15. 12. 2020

ISBN

0141-8130

Periodical

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Year of study

165

Number

Part B

State

Kingdom of the Netherlands

Pages from

2419

Pages to

2424

Pages count

6

URL

https://www.sciencedirect.com/science/article/pii/S0141813020348170

BibTex

@article{BUT165792,
  author="Adam {Jugl} and Andrea {Hurčíková} and Miloslav {Pekař}",
  title="Hysteresis during heating and cooling of hyaluronan solutions in water observed by means of ultrasound velocimetry",
  journal="INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES",
  year="2020",
  volume="165",
  number="Part B",
  pages="2419--2424",
  doi="10.1016/j.ijbiomac.2020.10.165",
  issn="0141-8130",
  url="https://www.sciencedirect.com/science/article/pii/S0141813020348170"
}