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MAZÁNKOVÁ, V. SŤAHEL, P. MATOUŠKOVÁ, P. BRABLEC, A. ČECH, J. PROKEŠ, L. BURŠÍKOVÁ, V. STUPAVSKÁ, M. LEHOCKÝ, M. OZALTIN, K. HUMPOLÍČEK, P. TRUNEC, D.
Original Title
Atmospheric Pressure Plasma Polymerized 2-Ethyl-2-oxazoline Based Thin Films for Biomedical Purposes
Type
journal article in Web of Science
Language
English
Original Abstract
Polyoxazoline thin coatings were deposited on glass substrates using atmospheric pressure plasma polymerization from 2-ethyl-2-oxazoline vapours. The plasma polymerization was performed in dielectric barrier discharge burning in nitrogen at atmospheric pressure. The thin films stable in aqueous environments were obtained at the deposition with increased substrate temperature, which was changed from 20 degrees C to 150 degrees C. The thin film deposited samples were highly active against both S. aureus and E. coli strains in general. The chemical composition of polyoxazoline films was studied by FTIR and XPS, the mechanical properties of films were studied by depth sensing indentation technique and by scratch tests. The film surface properties were studied by AFM and by surface energy measurement. After tuning the deposition parameters (i.e., monomer flow rate and substrate temperature), stable films, which resist bacterial biofilm formation and have cell-repellent properties, were achieved. Such antibiofouling polyoxazoline thin films can have many potential biomedical applications.
Keywords
antibiofouling; plasma polymer; oxazoline
Authors
MAZÁNKOVÁ, V.; SŤAHEL, P.; MATOUŠKOVÁ, P.; BRABLEC, A.; ČECH, J.; PROKEŠ, L.; BURŠÍKOVÁ, V.; STUPAVSKÁ, M.; LEHOCKÝ, M.; OZALTIN, K.; HUMPOLÍČEK, P.; TRUNEC, D.
Released
13. 11. 2020
Publisher
MDPI
Location
BASEL
ISBN
2073-4360
Periodical
Polymers
Year of study
12
Number
11
State
Swiss Confederation
Pages from
1
Pages to
15
Pages count
URL
https://www.mdpi.com/2073-4360/12/11/2679
Full text in the Digital Library
http://hdl.handle.net/11012/195835
BibTex
@article{BUT167298, author="Věra {Mazánková} and Pavel {Sťahel} and Petra {Skoumalová} and Antonín {Brablec} and Jan {Čech} and Lubomír {Prokeš} and Vilma {Buršíková} and Monika {Stupavská} and Marián {Lehocký} and Kadir {Ozaltin} and Petr {Humpolíček} and David {Trunec}", title="Atmospheric Pressure Plasma Polymerized 2-Ethyl-2-oxazoline Based Thin Films for Biomedical Purposes", journal="Polymers", year="2020", volume="12", number="11", pages="1--15", doi="10.3390/polym12112679", issn="2073-4360", url="https://www.mdpi.com/2073-4360/12/11/2679" }