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Publication detail
Marie Vysoká, V.L. Mazzarello, G. Delogu, I. Márová
Original Title
Antimicrobial activity of selected plant extracts and its possibility to effect human health
Type
abstract
Language
English
Original Abstract
This study was designed to evaluate the antimicrobial activity and cytotoxicity of selected plant extracts and its possibility to effect human health. Herbal medicines are used widely because of their potent therapeutic efficacy, antioxidant activities and no side effects. In this study, tested samples of herbs were prepared as water extracts and essential oils. All extracts were prepared from dry samples of Curcumin, Euterpe oleracea, Origanum vulgare, Panax Ginseng, Syzygium aromaticum and Zingiber officinale. Antimicrobial effect was tested on Staphylococcus aureus, Candida glabrata and Escherichia coli. Cytotoxicity was tested in by colorimetric MTT test on keratinocytes HaCaT and B16F1 and also on other cell lines, e.g. Caco-2, Raji. In all extracts was detected concentration dependent antimicrobial effect. Apoptosis, the cell’s natural mechanism for death, is a promising target for anticancer therapy. The hallmarks of cancer are present in all cancer cells regardless of the cause or type; these include uncontrolled growth, angiogenesis and apoptosis evasion. The prevention of cancer is one of the main functions of apoptosis. In this study was tested the apoptotic effects of selected plant extracts of Raji cell lines.
Keywords
antimicrobial activity, Caco - 2, Raji, Mtt test, apoptosis
Authors
Released
26. 2. 2021
Publisher
Biotechnology & Biotechnological Equipment, Volume 35, Issue sup1 (2021)
ISBN
1314-3530
Periodical
Biotechnology and Biotechnological Equipment
Number
35(1)
State
United Kingdom of Great Britain and Northern Ireland
Pages from
25
Pages to
26
Pages count
1
URL
https://eurobiotech2020.eu/
BibTex
@misc{BUT169841, author="Marie {Vysoká} and Ivana {Márová}", title="Antimicrobial activity of selected plant extracts and its possibility to effect human health", year="2021", journal="Biotechnology and Biotechnological Equipment", number="35(1)", pages="25--26", publisher="Biotechnology & Biotechnological Equipment, Volume 35, Issue sup1 (2021)", doi="10.1080/13102818.2020.1871545", issn="1314-3530", url="https://eurobiotech2020.eu/", note="abstract" }