Publication detail

Skin protecting activity of microbial extracts

UHLÍŘOVÁ, R. BOČÁN, D. SKOUMALOVÁ, P. MÁROVÁ, I.

Original Title

Skin protecting activity of microbial extracts

Type

abstract

Language

English

Original Abstract

Microalgae and red yeast extracts contain a broad spectrum of compounds, which could serve as an alternative to conventional nutrient sour-ce. Moreover, the extracts contain antioxidants and can provide nutrition and protection of the skin.Presented work aims at preparation and characterization of liposome particles with complex aqueous and oil extracts of microbial origin. Active compounds as well as antioxidant activity and SPF were determined by HPLC and spectrophotometry. Most promising extracts were packed into liposome and PHB-liposome particles. Prepared particles were characterized by their encapsulation efficiency, particle size and poly-dispersity index together with colloidal stability. Antimicrobial activity was tested against S. epidermidis and E. coli. Prepared extracts and particles were evaluated by MTT assay on human keratinocytes HaCaT cell line whether they alter cell viability.Micro- and nanoparticles with encapsulated antioxidant and antimicrobial active compounds can enhance the effectiveness of cosmetics and pharmaceuticals. In this work, the potential use of liposome particles with natural microbial extracts in appropriate concentration was proposed. Liposomes regardless PHB enrichment are stable with desired properties and suitable for further application in cosmetics as well as in the food industry.

Keywords

Microalgae, red yeast, antioxidant activity, antimicrobial activity, cytotoxicity, liposomes

Authors

UHLÍŘOVÁ, R.; BOČÁN, D.; SKOUMALOVÁ, P.; MÁROVÁ, I.

Released

1. 12. 2021

ISBN

2564-615X

Periodical

The EuroBiotech Journal

Year of study

5

Number

s2

State

Republic of Italy

Pages from

84

Pages to

84

Pages count

112

BibTex

@misc{BUT175344,
  author="Renata {Uhlířová} and David {Bočán} and Petra {Skoumalová} and Ivana {Márová}",
  title="Skin protecting activity of microbial extracts",
  year="2021",
  journal="The EuroBiotech Journal",
  volume="5",
  number="s2",
  pages="84--84",
  issn="2564-615X",
  note="abstract"
}