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DZURICKÁ, L. MÁROVÁ, I.
Original Title
Liposomal particles functionalized by antimicrobial ac-tive compoundstive compounds
Type
abstract
Language
English
Original Abstract
Lipid nanoparticles have been developed with the progress innanotechnology and their unique properties have made themone of the most widely used nanoparticles. The presented workis focused on two types of nanostructured particles, liposomesand PHB-liposome particles. Materials were functionalizedby active compounds, thymol and vitamin E. Liposomes wereoverall tested for stability, gradual release of incorporatedsubstances in the model environment and biological activity.Liposomal size and colloid stability were defined by dynamiclight scattering and zeta-potential. Particles they were subject-ed to the characterization of gradual release using the spec-trophotometric method into model environments. Antimi-crobial activity and synergic effect against gram-positive andgram-negative strains of microorganisms were also evaluated.To assess whether prepared nanostructured materials are suit-able for further cosmetic applications, a cytotoxicity assay onthe HaCaT cell line was carried out. Functional liposomal par-ticles showed promising results for various applications as cos-metic preservation and pharmaceutical antimicrobial products.
Keywords
lipid nanoparticles, liposomes, antimicrobial com-pounds, encapsulation
Authors
DZURICKÁ, L.; MÁROVÁ, I.
Released
1. 2. 2023
Publisher
Sciendo
ISBN
2564-615X
Periodical
The EuroBiotech Journal
Year of study
7
Number
1
State
Republic of Italy
Pages from
32
Pages to
74
Pages count
41
URL
https://sciendo.com/article/10.2478/ebtj-2023-0004?fbclid=IwAR2vAcc-FphGdQ7pdyJCVBB48f__sOYw1kQyi64IXmJjs6YDLWfvWJAVI8w
BibTex
@misc{BUT184218, author="Lucia {Dzurická} and Ivana {Márová}", title="Liposomal particles functionalized by antimicrobial ac-tive compoundstive compounds", year="2023", journal="The EuroBiotech Journal", volume="7", number="1", pages="32--74", publisher="Sciendo", issn="2564-615X", url="https://sciendo.com/article/10.2478/ebtj-2023-0004?fbclid=IwAR2vAcc-FphGdQ7pdyJCVBB48f__sOYw1kQyi64IXmJjs6YDLWfvWJAVI8w", note="abstract" }