Publication detail

T1 mapping of myocardium in rats using self-gated golden-angle acquisition

VITOUŠ, J. JIŘÍK, R. STRAČINA, T. HENDRYCH, M. NÁDENÍČEK, J. MACÍČEK, O. TIAN, Y. KRÁTKÁ, L. DRAŽANOVÁ, E. NOVÁKOVÁ, M. BABULA, P. PANOVSKÝ, R. DIBELLA, E. STARČUK, Z.

Original Title

T1 mapping of myocardium in rats using self-gated golden-angle acquisition

Type

journal article in Web of Science

Language

English

Original Abstract

PurposeThe aim of this study is to design a method of myocardial T1 quantification in small laboratory animals and to investigate the effects of spatiotemporal regularization and the needed acquisition duration.MethodsWe propose a compressed-sensing approach to T1 quantification based on self-gated inversion-recovery radial two/three-dimensional (2D/3D) golden-angle stack-of-stars acquisition with image reconstruction performed using total-variation spatiotemporal regularization. The method was tested on a phantom and on a healthy rat, as well as on rats in a small myocardium-remodeling study.ResultsThe results showed a good match of the T1 estimates with the results obtained using the ground-truth method on a phantom and with the literature values for rats myocardium. The proposed 2D and 3D methods showed significant differences between normal and remodeling myocardium groups for acquisition lengths down to approximately 5 and 15 min, respectively.ConclusionsA new 2D and 3D method for quantification of myocardial T1 in rats was proposed. We have shown the capability of both techniques to distinguish between normal and remodeling myocardial tissue. We have shown the effects of image-reconstruction regularization weights and acquisition length on the T1 estimates.

Keywords

MRI, retrospective gating, cardiac, fibrosis, remodeling, T1, quantification

Authors

VITOUŠ, J.; JIŘÍK, R.; STRAČINA, T.; HENDRYCH, M.; NÁDENÍČEK, J.; MACÍČEK, O.; TIAN, Y.; KRÁTKÁ, L.; DRAŽANOVÁ, E.; NOVÁKOVÁ, M.; BABULA, P.; PANOVSKÝ, R.; DIBELLA, E.; STARČUK, Z.

Released

9. 10. 2023

Publisher

John Wiley and Sons

ISBN

0740-3194

Periodical

MAGNETIC RESONANCE IN MEDICINE

Year of study

91

Number

1

State

United States of America

Pages from

368

Pages to

380

Pages count

13

URL

https://onlinelibrary.wiley.com/doi/10.1002/mrm.29846

Full text in the Digital Library

http://hdl.handle.net/11012/244166

BibTex

@article{BUT184699,
  author="Jiří {Vitouš} and Radovan {Jiřík} and Tibor {Stračina} and Michal {Hendrych} and Jaroslav {Nádeníček} and Ondřej {Macíček} and Ye {Tian} and Lucie {Krátká} and Eva {Dražanová} and Marie {Nováková} and Petr {Babula} and Roman {Panovský} and Edward {DiBella} and Zenon {Starčuk}",
  title="T1 mapping of myocardium in rats using self-gated golden-angle acquisition",
  journal="MAGNETIC RESONANCE IN MEDICINE",
  year="2023",
  volume="91",
  number="1",
  pages="368--380",
  doi="10.1002/mrm.29846",
  issn="0740-3194",
  url="https://onlinelibrary.wiley.com/doi/10.1002/mrm.29846"
}