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LÁZŇOVSKÝ, J. BŘÍNEK, A. ZIKMUND, T. KAISER, J.
Original Title
Ex-vivo Evaluation of Newly Formed Bone After Lumbar Interbody Fusion Surgery Using X-ray Micro Computed Tomography
Type
conference paper
Language
English
Original Abstract
Many novel biomaterials are recently investigated for use in spinal fusion surgery, especially in lumbar interbody fusion. The X-ray microCT as a tool is widely used for evaluating how successfully those biomaterials can perform a vertebral fusion. However, the current methodologies of microCT image assessment are based on visual evaluation by the operator. In this paper, we propose a methodology for how such biomaterials can be investigated in pre-clinical studies by investigating fused vertebrae morphology. We utilized microCT scans of pigs’ fused vertebrae to develop a fully automatic approach, which can characterize the morphometry of the bone in the fused region. A surface mesh model was created to extract the newly formed bone tissue between fused vertebrae in the microCT data. Extracted bone tissue was consequently evaluated according to the selected morphometric parameters. Characterization of the newly formed bone properties in the intervertebral area can be utilized to evaluate the osteogenesis function of implants used in lumbar interbody fusion surgery.
Keywords
X-ray micro computed tomography; Intervertebral fusion; Image processing; Lumbar interbody fusion; Quantitative tomography
Authors
LÁZŇOVSKÝ, J.; BŘÍNEK, A.; ZIKMUND, T.; KAISER, J.
Released
20. 12. 2023
Publisher
Springer Nature Singapore
Location
Singapore
ISBN
978-981-16-6774-9
Book
Medical Imaging and Computer-Aided Diagnosis
1876-1100
Periodical
Lecture notes in Electrical Engineering
Year of study
810
State
United Kingdom of Great Britain and Northern Ireland
Pages from
101
Pages to
110
Pages count
10
URL
https://link.springer.com/chapter/10.1007/978-981-16-6775-6_9
BibTex
@inproceedings{BUT187030, author="Jakub {Lázňovský} and Adam {Břínek} and Tomáš {Zikmund} and Jozef {Kaiser}", title="Ex-vivo Evaluation of Newly Formed Bone After Lumbar Interbody Fusion Surgery Using X-ray Micro Computed Tomography", booktitle="Medical Imaging and Computer-Aided Diagnosis", year="2023", journal="Lecture notes in Electrical Engineering", volume="810", pages="101--110", publisher="Springer Nature Singapore", address="Singapore", doi="10.1007/978-981-16-6775-6\{_}9", isbn="978-981-16-6774-9", issn="1876-1100", url="https://link.springer.com/chapter/10.1007/978-981-16-6775-6_9" }