Publication detail

In Vitro Cytotoxicity of Modified Hemostatic Cellulose Derivatives

DINPARVAR, S. SEDLÁŘ, M. VOJTOVÁ, L.

Original Title

In Vitro Cytotoxicity of Modified Hemostatic Cellulose Derivatives

Type

abstract

Language

English

Original Abstract

Hemostatic agents derived from oxidized cellulose are promising for promoting hemostasis and wound healing. This study investigates the cytotoxic effects of three modified cellulose derivatives where the first one is the commercially available material m-doc™, which is sodium-calcium salt of oxidized cellulose. M-doc™ is a patent-protected hemostatic active substance by the company Hemcon Medical Technologies, which is available in many commercial products serving for bleeding control (sprays, gels, nasal plugs, wound pads or IV dressings). The second derivative is a newly modified salt - pure sodium salt of oxidized cellulose (NaC) and the third is a sodium-zinc salt (ZnC). Oxidized cellulose derivatives were valued for their biocompatibility and Efficacy in wound healing and hemostasis. Evaluating their cytotoxicity is essential to ensure they do not have side effects on wound healing processes or hemostasis.

Keywords

oxidized cellulose, in vitro, L929 cells, m-doc

Authors

DINPARVAR, S.; SEDLÁŘ, M.; VOJTOVÁ, L.

Released

17. 9. 2024

Publisher

České vysoké učení technické v Praze

Location

Praha

ISBN

978-80-01-07334-6

Book

Biomateriály a jejich povrchy XVII.

Pages from

50

Pages to

51

Pages count

89

URL

https://www2.irsm.cas.cz/ext/biomaterialy/download/BIOMATERIALY_A_JEJICH_POVRCHY_XVII.pdf

BibTex

@misc{BUT189685,
  author="Sahar {Dinparvar} and Marian {Sedlář} and Lucy {Vojtová}",
  title="In Vitro Cytotoxicity of Modified Hemostatic Cellulose Derivatives",
  booktitle="Biomateriály a jejich povrchy XVII.",
  year="2024",
  pages="50--51",
  publisher="České vysoké učení technické v Praze",
  address="Praha",
  isbn="978-80-01-07334-6",
  url="https://www2.irsm.cas.cz/ext/biomaterialy/download/BIOMATERIALY_A_JEJICH_POVRCHY_XVII.pdf",
  note="abstract"
}