Course detail

Laboratory Classes in Organic Chemistry

FCH-BAT_OCH_PAcad. year: 2011/2012

Practical training at isolation, separation and identification procedures used in organic laboratories within the frame of representative one-step or multi-step syntheses. Training of the basic lab techniques of the synthesis and the isolation of organic compounds.

Language of instruction

English

Number of ECTS credits

4

Mode of study

Not applicable.

Learning outcomes of the course unit

Laboratory equipment and glassware handling.
Synthesis of organic compounds in laboratory scale.
Health and safety at work in a chemical laboratory.

Prerequisites

The knowledge of basic laboratory practices and techniques (recrystallization, distillation, extraction, etc.).

Co-requisites

Not applicable.

Planned learning activities and teaching methods

Teaching methods depend on the type of course unit as specified in the article 7 of BUT Rules for Studies and Examinations.

Assesment methods and criteria linked to learning outcomes

Finish 10 laboratories at least, submit lab. reports and prepared compounds during the term.
Pass test(s) about practical and theoretical knowledges.

Course curriculum

Students are briefed by organization of laboratory and syntheses in detail during the first lab. Safety training is also realized. Students realize at least 10 syntheses of the following:
1. 4-Nitroaniline
2. Ethylbromide a tert-butylchloride (2) (SN mechanism, simple distillation)
3. Ethyl acetate (3) (esterification, simple distillation)
4. Pinacol and pinacolon
5. Benziliv acid
6. Chlorobenzene(diazotation and Sandmeyer reaction, recrystallization)
7. Anhydride of cyclohex-4-ene-cis-dicarboxylic acid and Cyclohex-4-ene-cis-1,2-dicarboxylic acid (mechanism of Diels-Alder's reaction)
8. Phenacetine
9. Acid Red 150 (diazotation and copulation, recrystallization)
10. ß -Nitrostyrene (10a) a 1,5-difenylpenta-1,4-dien-3-one (10b)
11. Diphenylmethanol
12. 2-(-4-Toluoyl)benzoic acid
Labs at last week of the term are substitute for unqualified or sick students during the term.

Work placements

Not applicable.

Aims

Acquisition of the basic laboratory methods of the analysis and synthesis of organic substances.

Specification of controlled education, way of implementation and compensation for absences

Controlled personal attendance, lab. reports a test(s).

Recommended optional programme components

Not applicable.

Prerequisites and corequisites

Not applicable.

Basic literature

Not applicable.

Recommended reading

Sandler S.R., Karo W.: Sourcebook of Advanced Organic Laboratory Preparations. Academic Press, San Diego 1992. (EN)

Classification of course in study plans

  • Programme NPCP_CHM_INT Master's

    branch NPCO_CHM , 1 year of study, summer semester, not stated

  • Programme CKCP_CZV lifelong learning

    branch CKCO_CZV , 1 year of study, summer semester, not stated

Type of course unit

 

Laboratory exercise

78 hod., compulsory

Teacher / Lecturer