Course detail

Mass Spectrometry

FCH-MC_HMSAcad. year: 2012/2013

Physical bases of mass spectrometry, MS history. Ionization techniques - listing, development, description of contemporary used techniquies (electron ionization, chemical ionization, electrospray, chemical ionization at atmospheric pressure etc). Analyzers in mass spectrometry (static - magnetic, elctrostatic, quadrupole, 3D- and linear ion trap, Time-of-Flight, ion cyclotron resonance, orbitrap). Detectors and vacuum systems. Hyphenated and tandm techniquies. Interpretation of mass spectra with respect to the ionization technique applied.

Language of instruction

Czech

Number of ECTS credits

3

Mode of study

Not applicable.

Guarantor

prof. Ing. Josef Čáslavský, CSc.

Department

Institute of Chemistry and Technology of Environmental Protection (ÚCHTOŽP)

Learning outcomes of the course unit

Obtaining of information about mass spectrometry and about basic techniques of mass spectra interpretation

Prerequisites

Basic knowledge of physics - kinematics, the movement of charged particles in magnetic and electric field
Good knowledge of basic, inorganic, organic, physical and analytical chemistry

Co-requisites

Not applicable.

Planned learning activities and teaching methods

Teaching methods depend on the type of course unit as specified in the article 7 of BUT Rules for Studies and Examinations.

Assesment methods and criteria linked to learning outcomes

Examination - written test and oral examination

Course curriculum

1. Introduction to mass spectrometry, theoretical basics, natural isotopic distribution of elements and its importance in MS
2. Instrumentation of mass spectrometry
3. Ionization techniques in mass spectrometry
4. Mass analyzers
5. Hyphenated techniques (GC/MS, LC/MS, CE/MS, MS/MS)
6. Interpretation of mass spectra using electron ionization, fragmentation rules
7. Interpretation of mass spectra using soft ionization techniques
8. Practical applications of mass spectrometry

Work placements

Not applicable.

Aims

Introduction of mass spectrometry and its possibilities and limitations to students.

Specification of controlled education, way of implementation and compensation for absences

Not applicable.

Recommended optional programme components

Not applicable.

Prerequisites and corequisites

Not applicable.

Basic literature

Not applicable.

Recommended reading

Not applicable.

Classification of course in study plans

  • Programme NPCP_CHTOZP Master's

    branch NPCO_CHTOZP , 2 year of study, winter semester, compulsory-optional

  • Programme NKCP_CHTOZP Master's

    branch NKCO_CHTOZP , 2 year of study, winter semester, compulsory-optional

  • Programme CKCP_CZV lifelong learning

    branch CKCO_CZV , 1 year of study, winter semester, compulsory-optional

Type of course unit

 

Lecture

26 hod., optionally

Teacher / Lecturer

prof. Ing. Josef Čáslavský, CSc.