Course detail

Chemometrics

FCH-MC_CHMAcad. year: 2013/2014

Foundations of descriptive statistics. Point and interval estimations of random variables and their properties. Testing of statistical hypotheses, one sample tests, godness of fit tests. Random vectors, simultaneous and marginal distributions, the conditional density and probablistic functions. Numerical characteristics - the concepts of mean value, variance, covariance. Two sample tests. Multivariate normal distribution. The least square method, linear regression model and its generalizations and modifications. Intriduction to the non-linear regression, elements of regression diagnostics. Introduction to the variance analysis - the methods of Tuckey, Bartlett´s test, one and two factor ANOVA tests,The method of Schéffe and its application for determining of confidence zone in the linear regression model. Non-parametric tests - the sign test, Wilcoxon's test and Kruskal- Wallis test. Eigen-values and eigen-vectors, the principal component analysis and its application for data reduction. Foundations of factor analysis and its applications in the living environment research. Introduction to the discriminant analysis and its biomedicine applications. Introduction to the theory of neural nets, an alternative model to the classical statistics methods.

Language of instruction

Czech

Number of ECTS credits

4

Mode of study

Not applicable.

Learning outcomes of the course unit

A student will manage both theoretical and practical knowledge of mathematical statistics and its application in the evaluation of experimental data. He will be able of testing statistical hypotheses, application of regression models and application of more advanced multivariate statistical methods in biomedicine, living environment research, analytical chemistry and and other scientific branches.

Prerequisites

Foundations of mathematical analysis and linear algebra. Foundations of the probability theory and the most common continuous and discrete distributions.

Co-requisites

Not applicable.

Planned learning activities and teaching methods

The course uses teaching methods in form of Lecture - 2 teaching hours per week. The e-learning system (LMS Moodle) is available to teachers and students.

Assesment methods and criteria linked to learning outcomes

The classification is given by the examination consisting of the test and oral parts.

Course curriculum

1. The concept of a vector space with the linear independency and the basis. Elementary ways of giving planes and a lines in the space.
2. Polynomials and other elementary functions with their basic properties.
3. Matrices and elementary operations on matrices, the concept of the rank and determinant.
4. Elementary concepts of the calculus of functions of one variable - the limit, derivative and a continous function. A geometrical, physical and chemical meaning of the derivative, L'Hospital rule, a computation of a derivative of elementary functions by means of formulas and rules.
5. Inverse matrices, systems of linear equations, the Gauss elimination method.
6. The concept of a differential and its applications, Taylor polynomial and its applications.
7. The complete investigation of a function.
8. The indefinite integral and the elementary methods of its computation - the per partes and the substitution method.
9. The integration of a rational function and some irational functions, the universal trigonometric substitution.. The definite integral.
10. The improper integrals, geometrical and physical applications of a definite integral.
11. Elementary concepts of the theory of ordinary differential equations (ODE's) and the computation of the simpliest kinds of first-order ODE's, i.e. separable and linear equations.
12. Higher-order linear differential equations with constant coefficients. The method of indefinite coefficients for the special right side.
13. Foundations of the analytical geometry of planary and spatial quadratic objects, the least square method.

Work placements

Not applicable.

Aims

The aim of the course is to manage and apply the methods of mathematical staistings for processing of experimental data.

Specification of controlled education, way of implementation and compensation for absences

Participation on lectures is not compulsory. The course is finished by an examination consisting of the test and oral parts.

Recommended optional programme components

Not applicable.

Prerequisites and corequisites

Not applicable.

Basic literature

Not applicable.

Recommended reading

Not applicable.

Classification of course in study plans

  • Programme CKCP_CZV lifelong learning

    branch CKCO_CZV , 1 year of study, summer semester, compulsory-optional

  • Programme NPCP_SCH Master's

    branch NPCO_SCH , 1 year of study, summer semester, compulsory-optional
    branch NPCO_SCH , 2 year of study, summer semester, compulsory-optional

  • Programme NKCP_SCH Master's

    branch NKCO_SCH , 1 year of study, summer semester, compulsory-optional
    branch NKCO_SCH , 2 year of study, summer semester, compulsory-optional

Type of course unit

 

Lecture

26 hod., optionally

Teacher / Lecturer