The course is focused on the most advanced knowledge in technical diagnostics. Attention is devoted to clarification of incorporation of technical diagnostics into the product quality and to familiarization with the basic terms which are important for technical diagnostics. The diagnostic system, model and signal which belong among such terms are explained and discussed. Further, the basic diagnostic methods are described and discussed in detail. It is the diagnostics of deformation and pressure including the basic measurement and evaluation methods of the object temperature condition. Attention is devoted to the existing measuring instruments, measurement methods, and especially, to the monitored system status assessment and evaluation. The students are also familiarized with the standards and legislation valid in technical diagnostics. The possible qualification and its acquirement in technical diagnostics are also presented in detail. The course is completed with the exercises in which the selected topics are practiced using the examples from industrial practice. The results and conclusions are also discussed in the exercises. The Technical Diagnostics 1 and 2 courses in the master study continue this course. By doing so, the student will acquire state-of-the-art knowledge in the field of multiparametric technical diagnostics of machines and equipment, even within the Industry 4.0 initiative.