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FCH-BAT_OCH2Acad. year: 2023/2024
Halogen deivatives, nucleophilic substitution at saturated carbon atom, eleimination reactions. Alcohols phenols, polyhydroxyderivatives. Oxidation alcohols and phenols. Ethers, peroxides, epoxides, crown-ethers. Thiols, sulfides, sulfonic acids and their derivatives. Esters of inorganic acids. Amines, diazotation, arendiazonium salts and application, amine oxides. Diazo compounds, carbenes.Azides. Nitrocompounds. Organometallic compounds. Aldehydes and ketones, nucleophilic addition to the carbonyl group, aldolization reactions of aldehydes and ketones. Saccharides, structure and reactivity.Carboxylic acids, esterification, acyl halogenides, anhydrides, esters, amides. Halogen and amino acids, peptides, carbonic acid derivatives. Dicarbonyl compounds, unsaturated carbonyl compounds, quinones. Heterocyclic compounds.
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Syllabus
The course provides knowledge of basic organic chemistry in terms of mechanisms of organic reactions, basic physicochemical properties of selected types of organic compounds and the student learns the basic pillars of organic chemistry and organic synthesis. The course is divided into several chapters:
1. Halogenated derivatives of organic compounds, nucleophilic substitution on a saturated carbon atom, and elimination reactions. 2.-3. Alcohols, phenols, polyhydroxy compounds and their reactions. 4. Ethers, peroxides, epoxides. Thiols, sulphides, sulfonic acids and their derivatives.5.-6. Amines, their diazotation, formation of arendiazonium salts and their uses. Diazocompounds. Azides. Nitro compounds.7. Organometallic compounds and their reactions.8.-10. Carbonyl compounds - aldehydes and ketones, nucleophilic addition to the C=O group, aldolysis reactions of aldehydes and ketones.11.-13. Carboxylic acids and their functional derivatives: acyl halides, anhydrides, esters, amides.
Exercise
Teaching takes place according to the lecture syllabus of the course.