Course detail

Metrology and Experimental Data Processing

FCH-DAO_METAcad. year: 2023/2024

Definition of metrology, its importance for environmental analysis. Development and optimization of analytical methods; repeatability of analyses.. Metrological characteristics of analytical methods; limit of detection, limit of quantification, return, traceability, robustness, control long-term stability analytical method validation and uncertainty. Standard operating procedure and quality assurance of analytical results.

Language of instruction

English

Mode of study

Not applicable.

Entry knowledge

Not applicable.

Rules for evaluation and completion of the course

the knowledge will be tested by the group discussion - colloguium.

Aims

The aim is obtaining the knowledge on the metrology parameters related to trace analysis of componds and elements in various matrices.

Study aids

Not applicable.

Prerequisites and corequisites

Not applicable.

Basic literature

GRAFEN, A.. Modern statistics for the life sciences. Oxford: Oxford University Press, 2002. ISBN 01-992-5231-9. (EN)
MILLER, J. N. Statistics and chemometrics for analytical chemistry. 5th ed. Harlow: Pearson Prentice Hall, 2005, 268 s. ISBN 01-312-9192-0. (EN)
Ermer, J. and Miller, J. H. McB.: Method Validation in Pharmaceutical Analysis: a Guide to Best Prastice. Jonh Wiley & Sons, 2006, 418 s. ISBN: 978-3-527-31255-9. (EN)
HANRAHAN, G.: Environmental chemometrics: principles and modern application. CRC Press, 2009, 292 s. ISBN: 1420067966. (EN)
CHAN, Ch. Ch., LAM, H., ZHANG, X-M. Practical approaches to method validation and essential instrument qualification. Hoboken, N.J.: Wiley, c2010, xiv, 399 p. ISBN 04-701-2194-7. (EN)
BLIESNER, D. M. Validating chromatographic methods: a practical guide. Hoboken, N.J.: Wiley, c2006, viii, 291 p. ISBN 9780471741473. (EN)
REICHENBACHER, M. Challenges in analytical quality assurance. New York: Springer, 2011, p. cm. ISBN 978-3-642-16594-8. (EN)

Recommended reading

Not applicable.

Classification of course in study plans

  • Programme DPAP_FCH Doctoral 1 year of study, winter semester, compulsory-optional
  • Programme DKAP_FCH Doctoral 1 year of study, winter semester, compulsory-optional