Course detail

Biophysical Chemistry

FCH-MC_BFCHAcad. year: 2025/2026

The course focuses on the application of basic theoretical knowledge of physical chemistry to the biological systems. It represents a borderline course between physics, chemistry and biology, which allow obtaining molecular and structural perspective on biologically important and medically important pehnomena. Attention is drawn to an impact of the basic theoretical knowledge into analytical (advanced methods of study and interpretation of the structure and function of biopolymers) and application fields.

Language of instruction

Czech

Number of ECTS credits

4

Mode of study

Not applicable.

Guarantor

doc. Ing. Petr Sedláček, Ph.D.

Department

Institute of Physical and Applied Chemistry (ÚFSCH)

Entry knowledge

Not applicable.

Rules for evaluation and completion of the course

Exam: written and oral
Attendance to lectures is not required but is recommended.

Aims

The main aim of the course is to apply the basic knowledge and theories of physical chemistry (both from the thermodynamic and kinetic point of view) on the living systems and phenomena.
Completing the course will result in knowledge on the essential principles of chemical thermodynamics and kinetics and their application to biological systems.

Study aids

Not applicable.

Prerequisites and corequisites

Not applicable.

Basic literature

Kodíček M. Karpenko V.: Biofysikální chemie. Academia, 2000 (CS)

Recommended reading

Not applicable.

Classification of course in study plans

  • Programme NPCP_CHCHTE Master's 1 year of study, winter semester, compulsory
  • Programme NKCP_CHCHTE Master's 1 year of study, winter semester, compulsory

  • Programme NPCP_CHMA Master's

    specialization BF , 1 year of study, winter semester, compulsory
    specialization CHBL , 1 year of study, winter semester, compulsory

  • Programme NPCP_CHPL Master's 1 year of study, winter semester, compulsory
  • Programme NKCP_CHPL Master's 1 year of study, winter semester, compulsory
  • Programme NPCP_PCHBT Master's 1 year of study, winter semester, compulsory

Type of course unit

 

Lecture

26 hod., optionally

Teacher / Lecturer

doc. Ing. Petr Sedláček, Ph.D.

Syllabus

Syllabus divided to weekly given lectures:

1. Introduction to biophysical chemistry
2., 3. Role of molecular interactions
4., 5. Biological thermodynamics
6. Bioenergetics
7., 8. Phase transitions in biological systems
9. Binding equilibria
10. Function and properties of biological membranes
11. Non-equilibrium thermodynamics
12., 13. Biological kinetics

Guided consultation in combined form of studies

39 hod., optionally

Teacher / Lecturer

doc. Ing. Petr Sedláček, Ph.D.

Exercise

13 hod., compulsory

Teacher / Lecturer

doc. Ing. Petr Sedláček, Ph.D.

Syllabus