Course detail

Nuclear Magnetic Resonance

FCH-MC_NMRAcad. year: 2025/2026

The subject provides basic knowledge of advanced identification methods for analyzing the structure of new organic molecules. It deals with the physical foundations of NMR spectroscopy, 1D NMR 1H spectroscopy, 1D NMR 13C spectroscopy, 2D NMR spectroscopy methods, NMR spectra of selected groups of organic substances, procedures for interpreting spectra for individual molecules 

Language of instruction

Czech

Number of ECTS credits

4

Mode of study

Not applicable.

Guarantor

prof. Ing. Jozef Krajčovič, Ph.D.

Department

Institute of Chemistry and Technology of Environmental Protection (ÚCHTOŽP)

Entry knowledge

Fundamentals of Organic chemistry I+II, Analytical chemistry II, practice from instrumental analytical chemistry.

Rules for evaluation and completion of the course

Final written test. At least 50% of the questions must be answered.
Attendance at lectures is optional and is not controlled, but it is recommended.

Aims

The aim of this course is:
- to acquaint students with theoretical fundamentals and physical principles of Nuclear Magnetic Resonance (NMR)
- provide an overview of the current NMR instrumentation
- to introduce of students to the interpretation of NMR spectra
- demonstrating of application possibilities of NMR spectroscopy
At the end of the course students should be able to understand the spectra for NMR spectroscopy and structure analysis of organic compounds. The acquired knowledge enables to work both in research and practice of bioorganic and pharmaceutical chemistry, in control laboratories and state administration.

Study aids

Not applicable.

Prerequisites and corequisites

Not applicable.

Basic literature

Basic 1H- and 13C-NMR Spectroscopy, Metin Balci, 1st Edition, 2005 (CS)
Cvičení z NMR, Tomáš Pospíšil, Universita Palackého, 2015 (CS)
NMR Spectroscopy: Basic Principles, Concepts and Applications in Chemistry 3rd Edition, 2013, Harald Günther (EN)

Recommended reading

Not applicable.

Classification of course in study plans

  • Programme NKCP_ECHT Master's 2 year of study, winter semester, compulsory-optional
  • Programme NPCP_ECHT Master's 2 year of study, winter semester, compulsory-optional

Type of course unit

 

Guided consultation in combined form of studies

26 hod., optionally

Teacher / Lecturer

prof. Ing. Jozef Krajčovič, Ph.D.

Exercise

26 hod., compulsory

Teacher / Lecturer

prof. Ing. Jozef Krajčovič, Ph.D.

Syllabus

The subject provides basic knowledge of advanced identification methods for analyzing the structure of new organic molecules. It deals with the physical foundations of NMR spectroscopy, 1D NMR 1H spectroscopy, 1D NMR 13C spectroscopy, 2D NMR spectroscopy methods, NMR spectra of selected groups of organic substances, procedures for interpreting spectra for individual molecules 

1. Physical foundations of NMR spectroscopy 2. Basic parameters for assessment and interpretation of NMR spectra (signal multiplicity, Interaction constant, integral, chemical shift, etc.) 3. 1D NMR 1H spectroscopy, 1D NMR 13C spectroscopy, 2D NMR spectroscopy methods, 4. NMR spectra of selected groups of organic substances 5-13. procedures for interpreting NMR spectra for individual molecules