Advances in manufacturing and computing technology, and in particular in their interconnection, are bringing new approaches to product design and implementation in manufacturing processes and production systems. These are currently expressed in the Industry 4.0 concept, which implies that traditional tools for the necessary engineering activities are no longer sufficient for this development. Therefore, students are introduced to new approaches and methods: Manufacturing system such as intelligent system, basics of artificial intelligence, expert systems, neural networks, methods using knowledge bases. It is shown how to apply these methods and thus bring new quality for individual activities in the production system - product design and construction, technological preparation of production, group technology, production scheduling and management, production quality management.