Course detail

Pathological Physiology

FEKT-APFYAcad. year: 2010/2011

Pathological physiology is a science about ethiology and pathogenesis of diseases and pathological states. The ability of pathophysiological thinking makes possible an insight into the logical basis of clinical manifest diseases

Language of instruction

Czech

Number of ECTS credits

5

Mode of study

Not applicable.

Guarantor

Prof. MUDr. Anna Vašků, CSc.

Department

Department of Biomedical Engineering (UBMI)

Learning outcomes of the course unit

The ability acquired by training in pathophysiological thinking and by practical experience and experiments on animals to understand the basis of frequent pathological conditions and diseases.

Prerequisites

Knowledge at secondary school level and of completed subjects in the study area

Co-requisites

Not applicable.

Planned learning activities and teaching methods

Teaching methods depend on the type of course unit as specified in the article 7 of BUT Rules for Studies and Examinations.

Assesment methods and criteria linked to learning outcomes

Requirements are specified by guarantor’s regulation updated for every academic year.

Course curriculum

Instruction will proceed from general pathological processes to special pathophysiological states. In practical instruction the dynamics of some pathological conditions will be demonstrated on animal models.

Work placements

Not applicable.

Aims

To explain the basic principles of ethiopathological thinking with regard to diseases and pathological states.

Specification of controlled education, way of implementation and compensation for absences

Extent and forms are specified by guarantor‘ s regulation updated for every academic year.

Recommended optional programme components

Not applicable.

Prerequisites and corequisites

Not applicable.

Basic literature

KAŇKOVÁ, Kateřina et al. Patologická fyziologie pro bakalářské studijní programy. Brno: MU Brno, 2003. ISBN 80-2103-112-3. (CS)
VAŠKŮ, Anna et al. Praktikum z patologické fyziologie. 1. vyd. Brno: MU Brno, 2000. ISBN 80-210-2318-X. (CS)

Recommended reading

Not applicable.

Classification of course in study plans

  • Programme BTBIO-A Bachelor's

    branch A-BTB , 1 year of study, summer semester, compulsory

Type of course unit

 

Lecture

26 hod., compulsory

Teacher / Lecturer

Prof. MUDr. Anna Vašků, CSc.

Syllabus

1. The field of pathological physiology – health and disease – ethiology and pathogenesis.
2. External factors of the origin of diseases – physical, chemical and biological pathogenic factors.
3. InflammationThe cell and cellular interactions in pathogenic tissue damage. Healing of wounds. Malignant transformation.
4. Immunity system disorders – immunodeficiency, hypersensitiveness, autoimmunity
5. Fundamentals of genetics – monogenous vs. civilisation diseases
6. Pathophysiology of hematogenesis
7. Pathophysiology of the cardiovascular system
8. Pathophysiology of the respiratory system
9. Pathophysiology of the excretory system
10. Pathophysiology of the digestive system
11. Pathophysiology of hormones
12. Pathophysiology of the nervous and muscular system

Laboratory exercise

26 hod., compulsory

Teacher / Lecturer

Prof. MUDr. Anna Vašků, CSc.

Syllabus

1. Principles of work with animals
2. Radiation syndrome I
3. Radiation syndrome II
4. An experimental stomach ulcer
5. Renal ischemic disease
6. Experimental venous thrombosis
7. EKG and arythmia on animal models
8. Spirometric examination of lungs
9. Basics of DNA diagnostics - detection of I/D ACE polymorphism
10. Basics of hematological diagnostics
11. Experimental alloxane diabetes
12. Glucose tolerance test
13. Skin conductivity