study programme

Biophysical Chemistry

Original title in Czech: Biofyzikální chemieFaculty: FCHAbbreviation: DKCP_BCHAcad. year: 2024/2025

Type of study programme: Doctoral

Study programme code: P0531D130045

Degree awarded: Ph.D.

Language of instruction: Czech

Accreditation: 8.10.2019 - 8.10.2029

Mode of study

Combined study

Standard study length

4 years

Programme supervisor

Doctoral Board

Fields of education

Area Topic Share [%]
Chemistry Without thematic area 100

Issued topics of Doctoral Study Program

  1. Modelling of transport phenomena in biological environment

    The development of various drug delivery systems is an area of active research. This research is focused mainly on chemical, biochemical, or physiological aspects. The movement of a delivery system in human body, to the point of the drug action is much less investigated. The drug transport to the targeted site where the drug’s chemical action should take place is essential for its proper function. This study will be therefore aimed at mathematical modeling of this transport based either on published data or data collected at the supervisor’s laboratory. The work will be focused on the modeling of the diffusion of nano- and microparticles in model biological medium, especially in hydrogel or similar model of the extracellular matrix, or through biological membrane. These tasks will be solved using COMSOL packet. The tasks include also the construction of realistic structural model of the environment, embracing 3D structural features of real biological environments or of real tissues, and the modelling support of the microrheological experiments in hydrogels performed in the laboratory where this PhD study will be realized. The aim of this study is obtaining a feedback for the design of the drug delivery systems.

    Tutor: Klučáková Martina, prof. Ing., Ph.D.

  2. Study of the behaviour of crystalline active substances on a long-term time scale

    Study of stability and physicochemical phenomena of biologically active substances associated with their long-term storage. In particular, thermal analysis, powder rheology and microscopy methods will be used for this purpose.

    Tutor: Enev Vojtěch, doc. Ing., Ph.D.

Course structure diagram with ECTS credits

1. year of study, both semester
AbbreviationTitleL.Cr.Com.Compl.Hr. rangeGr.Op.
DC_BFCHBiophysical Chemistrycs0CompulsoryColyes
DC_BCHBMBiophysics and Biochemistry of Microorganismscs0Compulsory-optionalColyes
DC_BIOBioengineeringcs0Compulsory-optionalColyes
DC_F3DPhotochemistry and 3D printcs0Compulsory-optionalColyes
DC_ICHPAdvanced Immunochemistry cs0Compulsory-optionalColyes
DC_MTMaterial technology for the biophysical and medical applicationscs0Compulsory-optionalColyes
DC_BCHAdvanced Biochemistrycs0Compulsory-optionalColyes
DC_KPDAdvanced Colloid Chemistrycs0Compulsory-optionalColyes
DC_PFTAdvanced fluorescence techniquescs0Compulsory-optionalColyes
DC_PTTAdvanced techniques of thermal analysiscs0Compulsory-optionalColyes
DC_SMBSpecial molecular biotechnologycs0Compulsory-optionalColyes
DC_STISpecial techniques of instrumental analysiscs0Compulsory-optionalColyes
All the groups of optional courses
Gr. Number of courses Courses
1 2 - 11