Detail předmětu

Advanced Biochemistry

FCH-DA_BCHAk. rok: 2022/2023

The course focuses on the application of basic theoretical knowledge of physical chemistry to the biological systems. It represents a borderline course between physics, chemistry and biology, which allow obtaining molecular and structural perspective on biologically important and medically important pehnomena. Attention is drawn to an impact of the basic theoretical knowledge into analytical (advanced methods of study and interpretation of the structure and function of biopolymers) and application fields. Special topics: biothermodynamics: energetics of biological processes, Gibbs energy and its role in biological processes. Kinetics of biological processes, enzyme reactions, denaturation and renaturation. Non-covalent interactions in biological systems; 3D structure of biopolymers. Biomembranes. Water and hydratation. Biological polyelectrolytes.

Jazyk výuky

angličtina

Způsob a kritéria hodnocení

The results of the study are verified by colloquium (S.E.R. Art. 34 of the BUT Brno), ie a discussion about the subject matter connected with the preparation of a written work dealing with the specified topic of the subject in the range of about 10 text pages; the debate takes about 30 minutes.

Osnovy výuky

The course focuses on the application of basic theoretical knowledge of physical chemistry to the biological systems. It represents a borderline course between physics, chemistry and biology, which allow obtaining molecular and structural perspective on biologically important and medically important pehnomena. Attention is drawn to an impact of the basic theoretical knowledge into analytical (advanced methods of study and interpretation of the structure and function of biopolymers) and application fields. Special topics: biothermodynamics: energetics of biological processes, Gibbs energy and its role in biological processes. Kinetics of biological processes, enzyme reactions, denaturation and renaturation. Non-covalent interactions in biological systems; 3D structure of biopolymers. Biomembranes. Water and hydratation. Biological polyelectrolytes.

Základní literatura

Cooper A.: Biophysical Chemistry (EN)
Haynie, D.T. Biological Thermodynamics. Cambridge: Cambridge University Press, 2008. (EN)

Zařazení předmětu ve studijních plánech

  • Program DPAP_BCH doktorský 1 ročník, zimní semestr, povinně volitelný
  • Program DKAP_BCH doktorský 1 ročník, zimní semestr, povinně volitelný